FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term ESCRT IV complex ID (Ontology) GO:1990621 (Gene Ontology)
Definition An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.[ PubMed:20653365 PubMed:20696398 PubMed:21925211 PubMed:24456136 PubMed:25164817 PubMed:26775243 ]
Also Known As "ESCRT-IV"
Comment
Links to Extrernal Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 ESCRT IV complex (all annotations which use CV term, excluding "NOT" statements)       1      2
     part_of | ESCRT IV complex       --       2
Spanning Tree (Parents/Children)
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endosome
 |__endosome membrane___________
 |__ESCRT complex_______________|
membrane                        |
 |__membrane protein complex____|
cytoplasmic vesicle membrane    |
 |__endosome membrane___________|
protein-containing complex      |
 |__ESCRT complex_______________|
 |__membrane protein complex____|
bounding membrane of organelle  |
 |__endosome membrane___________|
catalytic complex               |
 |__ATPase complex______________|
                                ESCRT IV complex  3 rec.
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Is a ESCRT complex
membrane protein complex
ATPase complex
Part of endosome membrane
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Synonyms
  • "ESCRT-IV" EXACT
    "vacuolar protein sorting-associated complex" RELATED
    "Vps4 complex" RELATED
    "Vps4-Vta1 complex" NARROW
    "VPS4A-VPS4B" NARROW
    "VPS4A/B complex" NARROW
    "Vta1-Vps4 complex" RELATED
Secondary IDs
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