FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term GATOR1 complex ID (Ontology) GO:1990130 (Gene Ontology)
Definition A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.[ PubMed:21900499 PubMed:23723238 PubMed:23974112 PubMed:25934700 PubMed:28199306 PubMed:29199950 ]
Also Known As "IML1 complex" ; "SEACIT complex"
Comment
Links to Extrernal Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 GATOR1 complex (all annotations which use CV term, excluding "NOT" statements)       1      3
     part_of | GATOR1 complex       --       3
Spanning Tree (Parents/Children)
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cellular_component
 |__protein-containing complex__
protein-containing complex      |
 |__Seh1-associated complex_____|
                                GATOR1 complex  4 rec.
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Is a protein-containing complex
Part of Seh1-associated complex
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Synonyms
  • "IML1 complex" EXACT
    "SEACIT complex" EXACT
Secondary IDs
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