General Information
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Term |
branched-chain alpha-ketoacid dehydrogenase complex |
ID (Ontology) |
GO:0160157 (Gene Ontology) |
Definition |
A multi-enzyme complex that catalyzes the oxidative decarboxylation of branched-chain alpha-ketoacids derived from L-leucine, L-isoleucine, and L-valine to branched-chain acyl-CoAs. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: branched-chain alpha-ketoacid dehydrogenase (E1, a heterotetramer of two alpha and two beta subunits), dihydrolipoyl transacylase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.[ PubMed:10464218 PubMed:10745006 PubMed:3593587 ] |
Also Known As |
"BCKD complex" ; "BKDH complex" |
Comment |
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Links to Extrernal Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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Data Class | Field | Records |
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Genes (FBgn) | GO_CELLULAR_COMPONENT | 4 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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Full annotation statements | Relevant FlyBase reports |
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Gene Groups | Genes |
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branched-chain alpha-ketoacid dehydrogenase complex (all annotations which use CV term, excluding "NOT" statements) | 1 | 4 | part_of | branched-chain alpha-ketoacid dehydrogenase complex | -- | 4 |
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