FB2024_04 , released June 25, 2024
FB2024_04 , released June 25, 2024
CV Term Report
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General Information
Term execution phase of apoptosis ID (Ontology) GO:0097194 (Gene Ontology)
Definition A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.[ PubMed:21760595 ]
Also Known As "execution phase of apoptotic process"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
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Relevant FlyBase reports
 Gene Groups Genes
 execution phase of apoptosis (all annotations which use CV term, excluding "NOT" statements)       1      3
     involved_in | execution phase of apoptosis       --       3
Spanning Tree (Parents/Children)
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biological_process
 |__cellular process___
programmed cell death  |
 |__apoptotic process__|
                       execution phase of apoptosis  27 rec.
                        |__cellular component disassembly involved in execution phase of apoptosis 17 rec.
                        |   |__apoptotic nuclear changes(+) 17 rec.
                        |__phosphatidylserine exposure on apoptotic cell surface 2 rec.
                        |   |__regulation of phosphatidylserine exposure on apoptotic cell surface(+)
                        |__regulation of execution phase of apoptosis 4 rec.
                            |__negative regulation of execution phase of apoptosis(+) 1 rec.
                            |__positive regulation of execution phase of apoptosis
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Is a cellular process
Part of apoptotic process
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Synonyms
  • "apoptosis" NARROW
    "execution phase of apoptotic process" EXACT
Secondary IDs
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