FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term apoptotic signaling pathway ID (Ontology) GO:0097190 (Gene Ontology)
Definition The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
Also Known As "apoptotic signalling pathway" ; "induction of apoptosis by extracellular signals"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       6
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 apoptotic signaling pathway (all annotations which use CV term, excluding "NOT" statements)       6
     involved_in | apoptotic signaling pathway       6
Spanning Tree (Parents/Children)
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cell communication
 |__signal transduction_________
cellular process                |
 |__signal transduction_________|
programmed cell death           |
 |__apoptotic process___________|
signaling                       |
 |__signal transduction_________|
regulation of cellular process  |
 |__signal transduction_________|
cellular response to stimulus   |
 |__signal transduction_________|
                                apoptotic signaling pathway  62 rec.
                                 |__apoptosome assembly
                                 |   |__regulation of apoptosome assembly(+)
                                 |__extrinsic apoptotic signaling pathway 10 rec.
                                 |   |__B cell receptor apoptotic signaling pathway
                                 |   |__death-inducing signaling complex assembly(+)
                                 |   |__extrinsic apoptotic signaling pathway in absence of ligand(+) 3 rec.
                                 |   |__extrinsic apoptotic signaling pathway via death domain receptors(+) 3 rec.
                                 |   |__fibroblast growth factor receptor apoptotic signaling pathway
                                 |   |__regulation of extrinsic apoptotic signaling pathway(+) 4 rec.
                                 |   |__ripoptosome assembly involved in extrinsic apoptotic signaling pathway
                                 |__granzyme-mediated apoptotic signaling pathway
                                 |__hormone-mediated apoptotic signaling pathway
                                 |__intrinsic apoptotic signaling pathway 27 rec.
                                 |   |__intrinsic apoptotic signaling pathway by p53 class mediator(+) 7 rec.
                                 |   |__intrinsic apoptotic signaling pathway in response to DNA damage(+) 15 rec.
                                 |   |__intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(+) 7 rec.
                                 |   |__intrinsic apoptotic signaling pathway in response to hypoxia(+)
                                 |   |__intrinsic apoptotic signaling pathway in response to nitrosative stress(+)
                                 |   |__intrinsic apoptotic signaling pathway in response to osmotic stress(+)
                                 |   |__intrinsic apoptotic signaling pathway in response to oxidative stress(+) 2 rec.
                                 |   |__regulation of intrinsic apoptotic signaling pathway(+) 8 rec.
                                 |__mitochondrial outer membrane permeabilization 5 rec.
                                 |   |__regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(+) 3 rec.
                                 |__regulation of apoptotic signaling pathway 33 rec.
                                 |   |__negative regulation of apoptotic signaling pathway(+) 24 rec.
                                 |   |__positive regulation of apoptotic signaling pathway(+) 7 rec.
                                 |   |__regulation of extrinsic apoptotic signaling pathway(+) 4 rec.
                                 |   |__regulation of intrinsic apoptotic signaling pathway(+) 8 rec.
                                 |__release of cytochrome c from mitochondria 5 rec.
                                     |__regulation of release of cytochrome c from mitochondria(+) 3 rec.
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Is a signal transduction
Part of apoptotic process
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Synonyms
  • "apoptotic signalling pathway" EXACT
    "induction of apoptosis by extracellular signals" EXACT
Secondary IDs
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