FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term protein-arginine omega-N symmetric methyltransferase activity ID (Ontology) GO:0035243 (Gene Ontology)
Definition Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.[ EC:2 PubMed:14705965 ]
Also Known As "protein arginine omega-N symmetric methylase activity" ; "protein arginine omega-N symmetric methyltransferase activity"
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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Relevant FlyBase reports
 Genes
 protein-arginine omega-N symmetric methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       3
     enables | protein-arginine omega-N symmetric methyltransferase activity       3
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protein methyltransferase activity_____
arginine N-methyltransferase activity__|
                                       protein-arginine N-methyltransferase activity
                                        |__protein-arginine omega-N symmetric methyltransferase activity  3 rec.
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Is a protein-arginine N-methyltransferase activity
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Synonyms
  • "protein arginine omega-N symmetric methylase activity" EXACT
    "protein arginine omega-N symmetric methyltransferase activity" EXACT
    "S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming)" RELATED[ EC:2 ]
    "type II PRMT activity" RELATED
    "type II protein arginine methyltransferase activity" RELATED
Secondary IDs
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EC:2.1.1.320
Reactome:R-HSA-6804383 "PRMT5 methylates TP53"
RESID:AA0067
RESID:AA0069
RHEA:48108