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General Information
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| Term |
beta-catenin destruction complex |
ID (Ontology) |
GO:0030877 (Gene Ontology) |
| Definition |
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.[ PubMed:14600025 ] |
| Also Known As |
"APC-Axin-1-beta-catenin complex" ; "Axin-APC-beta-catenin-GSK3B complex" ; "BDC" (for all, see Synonyms field below) |
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Links to Extrernal Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 5 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Gene Groups | Genes |
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beta-catenin destruction complex (all annotations which use CV term, excluding "NOT" statements) | 3 | 5 | part_of | beta-catenin destruction complex | -- | 5 |
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Relationships
