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Term | NuRD complex | ID (Ontology) | GO:0016581 (Gene Ontology) |
Definition | An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.[ PubMed:10589671 PubMed:11743021 PubMed:17289569 ] | ||
Also Known As | "NRD complex" ; "nucleosome remodeling and histone deacetylation complex" | ||
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nucleoplasm |__histone deacetylase complex______ protein-containing complex | |__transcription regulator complex__| SWI/SNF superfamily-type complex | |__CHD-type complex_________________| nuclear protein-containing complex | |__histone deacetylase complex______| catalytic complex | |__histone deacetylase complex______| NuRD complex 9 rec. |__SHREC complex |
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Is a |
histone deacetylase complex transcription regulator complex CHD-type complex |
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