FB2024_04 , released June 25, 2024
FB2024_04 , released June 25, 2024
CV Term Report
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General Information
Term RISC complex ID (Ontology) GO:0016442 (Gene Ontology)
Definition A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.[ PubMed:10749213 PubMed:15145345 ]
Also Known As "RNA-induced silencing complex"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      99
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 RISC complex (all annotations which use CV term, excluding "NOT" statements)       1     99
     part_of | RISC complex       --      99
Spanning Tree (Parents/Children)
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  ribonucleoprotein complex
   |__RNAi effector complex
       |__RISC complex  100 rec.
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Is a RNAi effector complex
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Synonyms
  • "micro-ribonucleoprotein complex" RELATED
    "miRNP complex" RELATED
    "RNA-induced silencing complex" EXACT
Secondary IDs
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Wikipedia:RNA-induced_silencing_complex