FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term prefoldin complex ID (Ontology) GO:0016272 (Gene Ontology)
Definition A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.[ PubMed:17384227 PubMed:24068951 PubMed:9630229 ]
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       7
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 prefoldin complex (all annotations which use CV term, excluding "NOT" statements)       1      7
     part_of | prefoldin complex       --       7
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  cellular_component
   |__protein-containing complex
       |__prefoldin complex  8 rec.
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Synonyms
  • "GIM complex" NARROW
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Wikipedia:Prefoldin