FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term epsilon DNA polymerase complex ID (Ontology) GO:0008622 (Gene Ontology)
Definition A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.[ PubMed:15814431 PubMed:9745046 ]
Also Known As "DNA polymerase epsilon complex"
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Annotations
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       4
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Relevant FlyBase reports
 Gene Groups Genes
 epsilon DNA polymerase complex (all annotations which use CV term, excluding "NOT" statements)       1      4
     part_of | epsilon DNA polymerase complex       --       4
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nucleus
 |__nuclear protein-containing complex__________________________
chromosome                                                      |
 |__nuclear chromosome__________________________________________|
nuclear lumen                                                   |
 |__nuclear chromosome__________________________________________|
protein-containing complex                                      |
 |__nuclear protein-containing complex__________________________|
transferase complex, transferring phosphorus-containing groups  |
 |__DNA polymerase complex______________________________________|
intracellular protein-containing complex                        |
 |__DNA polymerase complex______________________________________|
                                                                epsilon DNA polymerase complex  5 rec.
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Is a DNA polymerase complex
nuclear protein-containing complex
Part of nuclear chromosome
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Synonyms
  • "DNA polymerase epsilon complex" EXACT
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