FB2024_04 , released June 25, 2024
FB2024_04 , released June 25, 2024
CV Term Report
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General Information
Term Notch signaling pathway ID (Ontology) GO:0007219 (Gene Ontology)
Definition The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Also Known As "N signaling pathway" ; "N signalling pathway" ; "Notch receptor signaling pathway" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      25
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 Notch signaling pathway (all annotations which use CV term, excluding "NOT" statements)       4     25
     involved_in | Notch signaling pathway       --      25
Spanning Tree (Parents/Children)
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  signal transduction
   |__cell surface receptor signaling pathway
       |__Notch signaling pathway  101 rec.
           |__Notch receptor processing, ligand-dependent 4 rec.
           |__Notch signaling involved in heart development
           |   |__Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation
           |__Notch signaling pathway involved in arterial endothelial cell fate commitment
           |__Notch signaling pathway involved in camera-type eye photoreceptor fate commitment
           |__Notch signaling pathway involved in forebrain neuroblast division
           |__Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment
           |__Notch signaling pathway involved in somitogenesis
           |   |__regulation of Notch signaling pathway involved in somitogenesis(+)
           |__positive regulation of transcription of Notch receptor target
           |__regulation of Notch signaling pathway 85 rec.
               |__negative regulation of Notch signaling pathway(+) 43 rec.
               |__positive regulation of Notch signaling pathway 47 rec.
               |__regulation of Notch signaling pathway involved in somitogenesis(+)
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Is a cell surface receptor signaling pathway
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Synonyms
  • "N signaling pathway" EXACT
    "N signalling pathway" EXACT
    "Notch receptor signaling pathway" EXACT
    "Notch receptor signalling pathway" EXACT
    "Notch signalling pathway" EXACT
    "Notch-receptor signaling pathway" EXACT
    "Notch-receptor signalling pathway" EXACT
Secondary IDs
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Wikipedia:Notch_signaling_pathway