FB2024_02 , released April 23, 2024
FB2024_02 , released April 23, 2024
CV Term Report
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General Information
Term proteolysis ID (Ontology) GO:0006508 (Gene Ontology)
Definition The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
Also Known As "peptidolysis"
Comment
Links to Extrernal Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS     489
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 proteolysis (all annotations which use CV term, excluding "NOT" statements)      56    489
     involved_in | proteolysis       --     479
 NOT | involved_in | proteolysis       --       6
Spanning Tree (Parents/Children)
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macromolecule metabolic process____________
primary metabolic process__________________|
organonitrogen compound metabolic process__|
                                           protein metabolic process
                                            |__proteolysis  991 rec.
                                                |__membrane protein proteolysis 14 rec.
                                                |   |__membrane protein ectodomain proteolysis(+) 10 rec.
                                                |   |__membrane protein intracellular domain proteolysis(+) 5 rec.
                                                |   |__membrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                |__protein processing 81 rec.
                                                |   |__activation of plasma proteins involved in acute inflammatory response
                                                |   |__CAAX-box protein processing 7 rec.
                                                |   |__dibasic protein processing(+)
                                                |   |__mitochondrial protein processing(+) 9 rec.
                                                |   |__Notch receptor processing, ligand-independent
                                                |   |__protein autoprocessing 6 rec.
                                                |   |__protein processing in phagocytic vesicle(+)
                                                |   |__protein splicing(+) 1 rec.
                                                |   |__regulation of protein processing(+) 5 rec.
                                                |   |__signal peptide processing(+) 11 rec.
                                                |   |__signaling receptor ligand precursor processing(+) 17 rec.
                                                |   |__vacuolar protein processing 1 rec.
                                                |   |__zymogen activation(+) 9 rec.
                                                |__proteolysis involved in protein catabolic process 390 rec.
                                                |   |__acrosome matrix dispersal
                                                |   |__mannoprotein catabolic process
                                                |   |__membrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                |   |__modification-dependent protein catabolic process(+) 340 rec.
                                                |   |__proteasomal protein catabolic process(+) 293 rec.
                                                |   |__protein quality control for misfolded or incompletely synthesized proteins(+) 6 rec.
                                                |   |__proteolysis associated with antigen processing and presentation(+)
                                                |   |__regulation of proteolysis involved in protein catabolic process(+) 81 rec.
                                                |   |__ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
                                                |__regulation of proteolysis 121 rec.
                                                |   |__negative regulation of proteolysis(+) 41 rec.
                                                |   |__positive regulation of proteolysis(+) 64 rec.
                                                |   |__regulation of membrane protein ectodomain proteolysis(+) 1 rec.
                                                |   |__regulation of peptidase activity(+) 3 rec.
                                                |   |__regulation of protein processing(+) 5 rec.
                                                |   |__regulation of proteolysis involved in protein catabolic process(+) 81 rec.
                                                |__self proteolysis 1 rec.
                                                    |__calcium-dependent self proteolysis
                                                    |__sodium-dependent self proteolysis
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Is a protein metabolic process
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Synonyms
  • "ATP-dependent proteolysis" NARROW
    "peptidolysis" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Wikipedia:Proteolysis