FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term alpha DNA polymerase:primase complex ID (Ontology) GO:0005658 (Gene Ontology)
Definition A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a smal stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.[ PubMed:11395402 PubMed:26975377 ]
Also Known As "DNA polymerase alpha:primase complex" ; "heterotetrameric polymerase alpha holoenzyme"
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Annotations
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       4
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Relevant FlyBase reports
 Gene Groups Genes
 alpha DNA polymerase:primase complex (all annotations which use CV term, excluding "NOT" statements)       1      4
     part_of | alpha DNA polymerase:primase complex       --       4
Spanning Tree (Parents/Children)
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DNA-directed RNA polymerase complex
 |__nuclear DNA-directed RNA polymerase complex_________________
replisome                                                       |
 |__nuclear replisome___________________________________________|
nuclear replication fork                                        |
 |__nuclear replisome___________________________________________|
transferase complex, transferring phosphorus-containing groups  |
 |__DNA polymerase complex______________________________________|
nuclear protein-containing complex                              |
 |__nuclear replisome___________________________________________|
 |__nuclear DNA-directed RNA polymerase complex_________________|
intracellular protein-containing complex                        |
 |__DNA polymerase complex______________________________________|
                                                                alpha DNA polymerase:primase complex  5 rec.
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Is a DNA polymerase complex
nuclear DNA-directed RNA polymerase complex
Part of nuclear replisome
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Synonyms
  • "DNA polymerase alpha:primase complex" EXACT
    "heterotetrameric polymerase alpha holoenzyme" EXACT
    "pol-prim" RELATED
    "primosome" BROAD
Secondary IDs
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