FB2024_04 , released June 25, 2024
FB2024_04 , released June 25, 2024
CV Term Report
Help Close All Open All
General Information
Term monooxygenase activity ID (Ontology) GO:0004497 (Gene Ontology)
Definition Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.[ ISBN:0198506732 ]
Comment
Links to Extrernal Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      90
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 monooxygenase activity (all annotations which use CV term, excluding "NOT" statements)       7     90
     enables | monooxygenase activity       --      90
 NOT | enables | monooxygenase activity       --       2
Spanning Tree (Parents/Children)
Only view relationship: 
  catalytic activity
   |__oxidoreductase activity
       |__monooxygenase activity  123 rec.
           |__2-hydroxyisobutyrate 3-monooxygenase activity
           |__2-hydroxypyridine 5-monooxygenase activity
           |__3-demethoxyubiquinol 3-hydroxylase activity 1 rec.
           |__3-hydroxybenzoate 2-monooxygenase activity
           |__4-chlorophenoxyacetate monooxygenase activity
           |__4-ketotorulene 3-hydroxylase activity
           |__4-methoxybenzoate monooxygenase (O-demethylating) activity
           |__4-nitrocatechol 4-monooxygenase activity
           |__20-aldehyde-leukotriene B4 20-monooxygenase activity
           |__20-hydroxy-leukotriene B4 omega oxidase activity
           |__acyl-lipid omega-(9-4) desaturase activity
           |__adonirubin 3-hydroxylase activity
           |__all-trans retinoic acid 18-hydroxylase activity
           |__ammonia monooxygenase activity
           |__androst-4-ene-3,17-dione monooxygenase activity
           |__arachidonic acid monooxygenase activity
           |   |__arachidonic acid epoxygenase activity(+)
           |__beta-carotene 3-hydroxylase activity
           |__beta-cryptoxanthin hydroxylase activity
           |__canthaxanthin 3-hydroxylase activity
           |__carotene beta-ring hydroxylase activity
           |__carotene epsilon hydroxylase activity
           |   |__alpha-carotene epsilon hydroxylase activity
           |   |__zeinoxanthin epsilon hydroxylase activity
           |__catechol oxidase activity 6 rec.
           |__cholesterol 7-desaturase (NAD(P)H) activity 1 rec.
           |__coumarin 7-hydroxylase activity
           |__deoxyhypusine monooxygenase activity 1 rec.
           |__dibenzothiophene-5,5-dioxide monooxygenase activity
           |__echinenone 3-hydroxylase activity
           |__estradiol 6-beta-monooxygenase activity
           |__eupatolide synthase activity
           |__fatty acid in-chain hydroxylase activity
           |__ferulate 5-hydroxylase activity
           |__inositol oxygenase activity 1 rec.
           |__jasmonoyl-isoleucine-12-hydroxylase activity
           |__linoleic acid epoxygenase activity
           |__luciferin monooxygenase activity
           |   |__Cypridina-luciferin 2-monooxygenase activity
           |   |__Latia-luciferin monooxygenase (demethylating) activity
           |   |__Oplophorus-luciferin 2-monooxygenase activity
           |   |__Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
           |   |__Renilla-luciferin 2-monooxygenase activity
           |   |__Watasenia-luciferin 2-monooxygenase activity
           |__methyl tertiary butyl ether 3-monooxygenase activity
           |__naphthalene hydroxylase activity
           |__nitrilotriacetate monooxygenase activity
           |__ornithine N5-monooxygenase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen 7 rec.
           |   |__6-hydroxy pseudo-oxynicotine monooxygenase activity
           |   |__C-4 methylsterol oxidase activity 2 rec.
           |   |__CMP-N-acetylneuraminate monooxygenase activity
           |   |__dihydroceramide fatty acyl 2-hydroxylase activity
           |   |__sphingolipid C4-monooxygenase activity
           |   |__tyrosinase activity 5 rec.
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 7 rec.
           |   |__(+)-abscisic acid 8'-hydroxylase activity
           |   |__(+)-delta-cadinene-8-hydroxylase activity
           |   |__(+)-taxifolin 5'-hydroxylase activity
           |   |__(-)-menthol monooxygenase activity
           |   |__(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity
           |   |__(5alpha)-campestan-3-one hydroxylase activity
           |   |__(11Z)-eicosenoate 14-hydroxylase activity
           |   |__(22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity
           |   |__(22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity
           |   |__(22S)-22-hydroxy-campesterol C-23 hydroxylase activity
           |   |__1,8-cineole 2-exo-monooxygenase activity
           |   |__1-deoxy-11-oxopentalenate oxygenase activity
           |   |__1-hydroxy-2-naphthoate hydroxylase activity
           |   |__1-hydroxy-2-oxolimonene 1,2-monooxygenase activity
           |   |__1-methylnaphthalene hydroxylase activity
           |   |__2,2',3-trihydroxybiphenyl monooxygenase activity
           |   |__2,2'-hydroxybiphenyl monooxygenase activity
           |   |__2,4-dichlorophenol 6-monooxygenase activity
           |   |__2,6-dihydroxypyridine 3-monooxygenase activity
           |   |__2-alpha-hydroxytaxusin 7-beta-hydroxylase activity
           |   |__2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity
           |   |__2-hydroxy-phenylacetate hydroxylase activity
           |   |__2-hydroxybiphenyl 3-monooxygenase activity
           |   |__2-hydroxycyclohexanone 2-monooxygenase activity
           |   |__2-hydroxyquinoline 8-monooxygenase activity
           |   |__2-isopropylphenol monooxygenase activity
           |   |__2-methylbutyronitrile hydroxylase activity
           |   |__2-methylnaphthalene hydroxylase activity
           |   |__2-methylpropionitrile hydroxylase activity
           |   |__2-nitrophenol 2-monooxygenase activity
           |   |__2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity
           |   |__2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity
           |   |__2-propylphenol monooxygenase activity
           |   |__3,5-xylenol methylhydroxylase activity
           |   |__3,9-dihydroxypterocarpan 6a-monooxygenase activity
           |   |__3-(3-hydroxyphenyl)propionate hydroxylase activity
           |   |__3-chlorotoluene monooxygenase activity
           |   |__3-epi-6-deoxocathasterone C-23 hydroxylase activity
           |   |__3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity
           |   |__3-HSA hydroxylase activity
           |   |__3-hydroxybenzoate 4-monooxygenase activity
           |   |__3-hydroxybenzoate 6-monooxygenase activity
           |   |__3-hydroxyphenylacetate 6-hydroxylase activity
           |   |__3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
           |   |__3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity
           |   |__3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity
           |   |__3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity
           |   |__4'-methoxyisoflavone 2'-hydroxylase activity
           |   |__4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity
           |   |__4-aminobenzoate 1-monooxygenase activity
           |   |__4-chlorobenzaldehyde oxidase activity
           |   |__4-hydroxyacetophenone monooxygenase activity
           |   |__4-hydroxybenzoate 1-hydroxylase activity
           |   |__4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity(+)
           |   |__4-hydroxybenzoate 3-monooxygenase activity
           |   |__4-hydroxyphenylacetaldehyde oxime monooxygenase activity
           |   |__4-hydroxyphenylacetate 1-monooxygenase activity
           |   |__4-hydroxypyridine-3-hydroxylase activity
           |   |__4-hydroxyquinoline 3-monooxygenase activity
           |   |__4-nitrophenol 2-monooxygenase activity
           |   |__4-nitrophenol 4-monooxygenase activity
           |   |__4-nitrotoluene monooxygenase activity
           |   |__4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity
           |   |__4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity
           |   |__4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity
           |   |__4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity
           |   |__4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity
           |   |__5-epi-aristolochene-1,3-dihydroxylase activity
           |   |__5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity
           |   |__5-pyridoxate dioxygenase activity
           |   |__6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
           |   |__6-hydroxynicotinate 3-monooxygenase activity
           |   |__6-oxocampestanol hydroxylase activity
           |   |__6-oxocineole dehydrogenase activity
           |   |__7-beta-hydroxytaxusin 2-alpha-hydroxylase activity
           |   |__7-oxateasterone synthase activity
           |   |__7-oxatyphasterol synthase activity
           |   |__9,10-dihydroxystearate hydroxylase activity
           |   |__9,10-epoxystearate hydroxylase activity
           |   |__9beta-pimara-7,15-diene oxidase activity
           |   |__11-oxo-beta-amyrin 30-oxidase activity
           |   |__11alpha-hydroxy-beta-amyrin dehydrogenase activity
           |   |__24-ethylidenelophenol 4alpha-methyl oxidase activity
           |   |__24-methylenecycloartanol 4alpha-methyl oxidase activity
           |   |__24-methylenelophenol methyl oxidase activity
           |   |__25-hydroxycholesterol 7alpha-hydroxylase activity
           |   |__27-hydroxycholesterol 7-alpha-monooxygenase activity
           |   |__30-hydroxy-beta-amyrin 11-hydroxylase activity
           |   |__abieta-7,13-dien-18-ol hydroxylase activity
           |   |__abieta-7,13-diene hydroxylase activity
           |   |__abietadienal hydroxylase activity
           |   |__albendazole monooxygenase activity
           |   |__alkene monooxygenase activity
           |   |__allocryptopine 6-hydroxylase activity
           |   |__alpha-amyrin 28-monooxygenase activity
           |   |__alpha-humulene 10-hydroxylase activity
           |   |__alpha-pinene monooxygenase [NADH] activity
           |   |__anandamide epoxidase activity(+)
           |   |__angelicin synthase activity
           |   |__anhydrotetracycline monooxygenase activity
           |   |__anthranilate 3-monooxygenase (deaminating) activity
           |   |__anthraniloyl-CoA monooxygenase activity
           |   |__apigenin-7,4'-dimethyl ether 6-hydroxylase activity
           |   |__aurachin C monooxygenase activity
           |   |__benzoate 4-monooxygenase activity
           |   |__benzoyl-CoA 3-monooxygenase activity
           |   |__beta-amyrin 11-oxidase activity
           |   |__beta-amyrin 30-monooxygenase activity
           |   |__beta-amyrin monooxygenase activity
           |   |__beta-carotene 2,2'-beta-hydroxylase activity
           |   |__bisphenol A hydroxylase A activity
           |   |__branched-chain dodecylbenzene sulfonate monooxygenase activity
           |   |__brassinolide synthase activity
           |   |__calcidiol 1-monooxygenase activity
           |   |__campest-4-en-3-one hydroxylase activity
           |   |__campestanol hydroxylase activity
           |   |__campesterol,NADPH:oxygen oxidoreductase activity
           |   |__carbon disulfide oxygenase activity
           |   |__chlorophenol 4-monooxygenase activity
           |   |__cholest-4-en-3-one 26-monooxygenase activity
           |   |__cholestanetriol 26-monooxygenase activity
           |   |__cholestanol hydroxylase activity
           |   |__cholesterol 7-alpha-monooxygenase activity
           |   |__cholesterol 24-hydroxylase activity
           |   |__coniferyl aldehyde 5-hydroxylase activity
           |   |__costunolide 3beta-hydroxylase activity
           |   |__costunolide synthase activity
           |   |__cyclohexanone monooxygenase activity
           |   |__cyclooctat-9-en-5,7-diol C18-monooxygenase activity
           |   |__cyclopentanone monooxygenase activity
           |   |__CYP79F1 dihomomethionine monooxygenase activity
           |   |__CYP79F1 tetrahomomethionine monooxygenase activity
           |   |__CYP79F1 trihomomethionine monooxygenase activity
           |   |__cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity
           |   |__cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity
           |   |__cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity
           |   |__cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity
           |   |__cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity
           |   |__dammarenediol 12-hydroxylase activity
           |   |__dehydroabietadienal hydroxylase activity
           |   |__dehydroabietadienol hydroxylase activity
           |   |__Delta12-linoleate epoxygenase activity
           |   |__deoxysarpagine hydroxylase activity
           |   |__dibenzothiophene monooxygenase activity
           |   |__dihydrochelirubine 12-monooxygenase activity
           |   |__dihydrosanguinarine 10-monooxygenase activity
           |   |__dimethyl sulfide monooxygenase activity
           |   |__dimethylsulfoxide oxygenase activity
           |   |__DMNT synthase activity
           |   |__emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity
           |   |__ent-cassa-12,15-diene 11-hydroxylase activity
           |   |__ent-cassadiene-C2-hydroxylase activity
           |   |__ent-isokaurene C2-hydroxylase activity
           |   |__ent-kaur-16-en-19-al oxidase activity
           |   |__ent-kaur-16-en-19-ol oxidase activity
           |   |__ent-kaurene oxidase activity
           |   |__eriodictyol 2-hydroxylase activity
           |   |__eriodictyol,NADPH:oxygen oxidoreductase activity
           |   |__FAD-dependent urate hydroxylase activity
           |   |__flaviolin monooxygenase activity
           |   |__flavonoid 3',5'-hydroxylase activity
           |   |__flavonoid 3'-monooxygenase activity
           |   |__fluorescent chlorophyll catabolite monooxygenase (deformylase) activity
           |   |__fraxetin 5-hydroxylase activity
           |   |__genkwanin 6-hydroxylase activity
           |   |__geraniol 10-hydroxylase activity
           |   |__germacrene A acid 8beta-hydroxylase activity
           |   |__hydroxyphenylacetonitrile 2-monooxygenase activity
           |   |__hypotaurine dehydrogenase activity
           |   |__imidazoleacetate 4-monooxygenase activity
           |   |__indole-3-carbonyl nitrile 4-hydroxylase activity
           |   |__indole-3-pyruvate monooxygenase activity
           |   |__indolin-2-one monooxygenase activity
           |   |__isobutylamine N-hydroxylase activity
           |   |__isoflavone 3'-hydroxylase activity
           |   |__isofucosterol hydroxylase activity
           |   |__isoleucine N-monooxygenase (oxime forming) activity
           |   |__isopimaradienal hydroxylase activity
           |   |__isopimaradienol hydroxylase activity
           |   |__ketosteroid monooxygenase activity
           |   |__kynurenine 3-monooxygenase activity 1 rec.
           |   |__L-lysine 6-monooxygenase (NADPH) activity
           |   |__L-phenylalanine N-monooxygenase activity
           |   |__leukotriene-E4 20-monooxygenase activity
           |   |__levopimaradienol hydroxylase activity
           |   |__limonene hydroxylase activity
           |   |__limonene monooxygenase activity(+)
           |   |__lithocholate 6beta-hydroxylase activity
           |   |__lupeol 28-monooxygenase activity
           |   |__lupeol 28-oxidase activity
           |   |__magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity
           |   |__melilotate 3-monooxygenase activity
           |   |__methane monooxygenase activity(+)
           |   |__methanesulfonate monooxygenase activity
           |   |__methyltetrahydroprotoberberine 14-monooxygenase activity
           |   |__N,N-dimethylaniline monooxygenase activity 2 rec.
           |   |__N-methylcoclaurine 3'-monooxygenase activity
           |   |__naringenin 2-hydroxylase activity
           |   |__nitric-oxide synthase activity 1 rec.
           |   |__octat-9-en-7-ol 5-monooxygenase activity
           |   |__oleate 12-hydroxylase activity
           |   |__orcinol 2-monooxygenase activity
           |   |__parthenolide 3beta-hydroxylase activity
           |   |__parthenolide synthase activity
           |   |__paspalicine synthase activity
           |   |__paspalinine synthase activity
           |   |__pentachlorophenol monooxygenase activity
           |   |__phenanthrene 1,2-monooxygenase activity
           |   |__phenanthrene 3,4-monooxygenase activity
           |   |__phenanthrene 9,10-monooxygenase activity
           |   |__phenol 2-monooxygenase activity
           |   |__phenylacetate hydroxylase activity
           |   |__phenylacetone monooxygenase activity
           |   |__phenylacetyl-CoA 1,2-epoxidase activity
           |   |__phosphatidylcholine 12-monooxygenase activity
           |   |__pinocembrin 2-hydroxylase activity
           |   |__piperitol synthase activity
           |   |__precorrin-3B synthase activity
           |   |__protopanaxadiol 6-hydroxylase activity
           |   |__protopine 6-monooxygenase activity
           |   |__psoralen synthase activity
           |   |__pyocyanin hydroxylase activity
           |   |__questin monooxygenase activity
           |   |__quinine 3-monooxygenase activity
           |   |__sakuranetin 6-hydroxylase activity
           |   |__salicylate 1-monooxygenase activity
           |   |__salicylate 5-hydroxylase activity
           |   |__scopoletin 8-hydroxylase activity
           |   |__senecionine N-oxygenase activity
           |   |__sesamin synthase activity
           |   |__sitosterol hydroxylase activity
           |   |__squalene monooxygenase activity
           |   |__sterol 14-demethylase activity
           |   |__styrene monooxygenase activity
           |   |__syn-pimaradiene 6beta-hydroxylase activity
           |   |__tabersonine 16-hydroxylase activity
           |   |__taxane 10-beta-hydroxylase activity
           |   |__taxane 13-alpha-hydroxylase activity
           |   |__taxifolin 8-monooxygenase activity
           |   |__taxoid 7beta-hydroxylase activity
           |   |__taxoid 14-beta-hydroxylase activity
           |   |__taxusin 2-alpha-hydroxylase activity
           |   |__tetrahydrofuran hydroxylase activity
           |   |__tocopherol omega-hydroxylase activity(+)
           |   |__tocotrienol omega-hydroxylase activity
           |   |__toluene 2-monooxygenase activity
           |   |__toluene 4-monooxygenase activity
           |   |__toluene-4-sulfonate monooxygenase activity
           |   |__toluene-sulfonate methyl-monooxygenase activity
           |   |__trans-cinnamate 2-monooxygenase activity
           |   |__trans-cinnamate 4-monooxygenase activity
           |   |__tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity(+)
           |   |__tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity(+)
           |   |__trimethylamine monooxygenase activity
           |   |__trimethyluric acid monooxygenase activity
           |   |__tyrosine N-monooxygenase activity
           |   |__ursolic aldehyde 28-monooxygenase activity
           |   |__valine N-monooxygenase (oxime forming) activity
           |   |__vanillate monooxygenase activity
           |   |__vinorine hydroxylase activity
           |   |__xylene monooxygenase activity
           |   |__zeaxanthin 2,2'-beta-hydroxylase activity
           |   |__zeaxanthin 2-beta-hydroxylase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen 5 rec.
           |   |__1-aminocyclopropane-1-carboxylate oxidase activity
           |   |__dopamine beta-monooxygenase activity 3 rec.
           |   |__peptidylglycine monooxygenase activity 1 rec.
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 5 rec.
           |   |__(+)-menthofuran synthase activity
           |   |__2,5-diketocamphane 1,2-monooxygenase
           |   |__2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity
           |   |__2-hydroxyisoflavanone synthase activity
           |   |__3,5 dichloro-THPH synthase activity
           |   |__3-chloro THPH synthase activity
           |   |__3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity
           |   |__3-hydroxyindolin-2-one monooxygenase activity
           |   |__4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity 1 rec.
           |   |__4-hydroxyphenylacetate 3-monooxygenase activity
           |   |__7-deoxyloganate 7-hydroxylase activity
           |   |__7-deoxyloganin 7-hydroxylase activity
           |   |__24-hydroxycholesterol 7alpha-hydroxylase activity
           |   |__aflatoxin B synthase activity
           |   |__alkanal monooxygenase (FMN-linked) activity
           |   |__alkanesulfonate monooxygenase activity
           |   |__aromatase activity
           |   |__ent-kaurenoic acid monooxygenase activity
           |   |__fatty acid omega-hydroxylase activity(+) 1 rec.
           |   |__flavanone 2-hydroxylase activity
           |   |__germacrene A hydroxylase activity
           |   |__glyceollin synthase activity
           |   |__heme oxygenase (decyclizing) activity 1 rec.
           |   |__indole-2-monooxygenase activity
           |   |__isoflavone 2'-hydroxylase activity
           |   |__leukotriene-B4 20-monooxygenase activity
           |   |__linalool 8-monooxygenase activity
           |   |__nitrilotriacetate monooxygenase activity (FMN-dependent)
           |   |__pipecolic acid N-hydroxylase
           |   |__pyrrole-2-carboxylate monooxygenase activity
           |   |__sterol 12-alpha-hydroxylase activity(+)
           |   |__taurochenodeoxycholate 6alpha-hydroxylase activity
           |   |__tryptophan N-monooxygenase activity
           |   |__uvaol dehydrogenase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1 rec.
           |   |__2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity
           |   |__3-ketosteroid 9-alpha-monooxygenase activity
           |   |__4-AD 9alpha-hydroxylase activity
           |   |__ADD 9alpha-hydroxylase activity
           |   |__alkane 1-monooxygenase activity 1 rec.
           |   |__arachidonic acid omega-hydroxylase activity
           |   |__atrazine N-dealkylase activity
           |   |__butane monooxygenase activity
           |   |__camphor 5-monooxygenase activity
           |   |__cholesterol monooxygenase (side-chain-cleaving) activity
           |   |__choline monooxygenase activity
           |   |__corticosterone 18-monooxygenase activity
           |   |__cyclohexane monooxygenase activity
           |   |__deethylatrazine monooxygenase activity
           |   |__deisopropylatrazine monooxygenase activity
           |   |__midchain alkane hydroxylase activity
           |   |__N-isopropylacetaniline monooxygenase activity
           |   |__spheroidene monooxygenase activity
           |   |__steroid 11-beta-monooxygenase activity
           |   |__zeaxanthin epoxidase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen 4 rec.
           |   |__glyceryl-ether monooxygenase activity
           |   |__mandelate 4-monooxygenase activity
           |   |__phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity
           |   |__phenylalanine 4-monooxygenase activity 2 rec.
           |   |__tryptophan 5-monooxygenase activity 2 rec.
           |   |__tyrosine 3-monooxygenase activity 1 rec.
           |__oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
           |   |__1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity
           |   |__2-mercaptobenzothiazole monooxygenase activity
           |   |__2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity
           |   |__6-hydroxy-2-mercaptobenzothiazole monooxygenase activity
           |   |__apo-beta-carotenoid-14',13'-dioxygenase activity
           |   |__arginine 2-monooxygenase activity
           |   |__chlorophyllide a oxygenase activity
           |   |__Cypridina-luciferin 2-monooxygenase activity
           |   |__hexadecyltrimethylammonium chloride monooxygenase activity
           |   |__isooctane monooxygenase activity
           |   |__L-lysine 6-monooxygenase (NADPH) activity
           |   |__lactate 2-monooxygenase activity
           |   |__lycopene cleavage oxygenase activity
           |   |__lysine 2-monooxygenase activity
           |   |__nitronate monooxygenase (FMN-linked) activity
           |   |__nitronate monooxygenase activity
           |   |__Oplophorus-luciferin 2-monooxygenase activity
           |   |__phenylalanine 2-monooxygenase activity
           |   |__Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
           |   |__Renilla-luciferin 2-monooxygenase activity
           |   |__tryptophan 2-monooxygenase activity
           |   |__Watasenia-luciferin 2-monooxygenase activity
           |__p-coumarate 3-hydroxylase activity
           |__phylloquinone monooxygenase (2,3-epoxidizing) activity
           |__progesterone 11-alpha-monooxygenase activity
           |__progesterone monooxygenase activity
           |__retinoic acid 4-hydroxylase activity
           |   |__all-trans retinoic acid 4-hydrolase activity
           |__secalciferol 1-monooxygenase activity
           |__steroid 9-alpha-monooxygenase activity
           |__steroid hydroxylase activity 5 rec.
           |   |__cholesterol 7-alpha-monooxygenase activity
           |   |__cholesterol 25-hydroxylase activity
           |   |__cholesterol 26-hydroxylase activity
           |   |__cholesterol monooxygenase (side-chain-cleaving) activity
           |   |__ecdysone 20-monooxygenase activity 1 rec.
           |   |__ecdysteroid 2-hydroxylase activity 1 rec.
           |   |__ecdysteroid 22-hydroxylase activity 1 rec.
           |   |__ecdysteroid 25-hydroxylase activity 1 rec.
           |   |__estrogen 2-hydroxylase activity
           |   |__estrogen 16-alpha-hydroxylase activity
           |   |__oxysterol 7-alpha-hydroxylase activity
           |   |__steroid 7-alpha-hydroxylase activity
           |   |__steroid 11-beta-monooxygenase activity
           |   |__steroid 17-alpha-monooxygenase activity
           |   |__steroid 21-monooxygenase activity(+)
           |   |__steroid 22-alpha hydroxylase activity
           |   |__sterol 12-alpha-hydroxylase activity(+)
           |   |__testosterone 6-beta-hydroxylase activity
           |   |__testosterone 15-alpha-hydroxylase activity
           |   |__testosterone 16-alpha-hydroxylase activity
           |__tert-butanol 2-monooxygenase activity
           |__testosterone 16-beta-hydroxylase activity
           |__thalianol hydroxylase activity
           |__thiophene-2-carbonyl-CoA monooxygenase activity
           |__tryptamine 4-monooxygenase activity
           |__vitamin D 23-hydroxylase activity
           |   |__1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity
           |   |__25-hydroxycholecalciferol-23-hydroxylase activity
           |__vitamin D 24-hydroxylase activity 1 rec.
           |   |__1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 1 rec.
           |   |__25-hydroxycholecalciferol-24-hydroxylase activity
           |__vitamin D 25-hydroxylase activity
               |__vitamin D3 25-hydroxylase activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a oxidoreductase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "hydroxylase activity" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-143468 "MEOS oxidizes ethanol to acetaldehyde"
Reactome:R-HSA-156526 "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO"
Reactome:R-HSA-211882 "CYP3A7 can 6beta-hydroxylate testosterone"
Reactome:R-HSA-211904 "CYP4F12 18-hydroxylates ARA"
Reactome:R-HSA-211910 "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation"
Reactome:R-HSA-211919 "CYP4F8 19-hydroxylates PGH2"
Reactome:R-HSA-211924 "CYP4B1 12-hydroxylates ARA"
Reactome:R-HSA-211929 "CYP2C19 5-hydroxylates omeprazole"
Reactome:R-HSA-211948 "CYP3A4 can N-demethylate loperamide"
Reactome:R-HSA-211951 "CYP1B1 4-hydroxylates EST17b"
Reactome:R-HSA-211959 "CYP3A43 6b-hydroxylates TEST"
Reactome:R-HSA-211960 "CYP2U1 19-hydroxylates ARA"
Reactome:R-HSA-211962 "CYP4F11 16-hydroxylates 3OH-PALM"
Reactome:R-HSA-211968 "CYP2W1 oxidises INDOL"
Reactome:R-HSA-211988 "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation"
Reactome:R-HSA-211991 "Cyclophosphamide is 4-hydroxylated by CYP2B6"
Reactome:R-HSA-212004 "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation"
Reactome:R-HSA-212005 "CYP2F1 dehydrogenates 3-methylindole"
Reactome:R-HSA-213175 "CYP3A4,5 oxidise AFB1 to AFXBO"
Reactome:R-HSA-215526 "CYP4F3 20-hydroxylates LTB4"
Reactome:R-HSA-2161795 "Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)"
Reactome:R-HSA-2161814 "Arachidonic acid is hydroxylated to 19-HETE by CYP(2)"
Reactome:R-HSA-2161890 "Arachidonic acid is epoxidated to 5,6-EET by CYP(4)"
Reactome:R-HSA-2161899 "Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)"
Reactome:R-HSA-2161940 "Arachidonic acid is hydroxylated to 20-HETE by CYP(3)"
Reactome:R-HSA-2162191 "DMPhOH is hydroxylated to MDMQ10H2 by DMPhOH monooxygenase"
Reactome:R-HSA-217258 "FMO2:FAD:Mg2+ S-oxidises MTZ"
Reactome:R-HSA-5423647 "CYP2A13 oxidises AFM1 to AFM1E"
Reactome:R-HSA-5423664 "CYP3A4,5 hydroxylates AFB1 to AFQ1"
Reactome:R-HSA-5423672 "CYP1A2, 3A4 oxidise AFB1 to AFNBO"
Reactome:R-HSA-5423678 "CYP1A2 hydroxylates AFB1 to AFM1"
Reactome:R-HSA-5602242 "Defective CYP2U1 does not omega-hydroxylate ARA"
Reactome:R-HSA-5602272 "Defective CYP4F22 does not 20-hydroxylate TrXA3"
Reactome:R-HSA-5602295 "CYP4F22 20-hydroxylates TrXA3"
Reactome:R-HSA-5605147 "Defective CYP1B1 does not 4-hydroxylate EST17b"
Reactome:R-HSA-5662662 "Tyrosinase oxidises tyrosine to dopaquinone"
Reactome:R-HSA-5662692 "Dopa is oxidized to dopaquinone by TYR"
Reactome:R-HSA-5663050 "DHI and DHICA polymerize forming eumelanin"
Reactome:R-HSA-6786239 "CYP4V2 omega-hydroxylates DHA to HDoHE"
Reactome:R-HSA-76354 "Vinyl chloride is oxidized to 2-Chloroethylene oxide"
Reactome:R-HSA-76373 "N-hydroxylation of 4-aminobiphenyl"
Reactome:R-HSA-76386 "CYP1A2 S-demethylates 6MMP"
Reactome:R-HSA-76397 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI)"
Reactome:R-HSA-76416 "Benzene is hydroxylated to phenol"
Reactome:R-HSA-76426 "N-atom dealkylation of caffeine"
Reactome:R-HSA-76434 "Dehalogenation of carbon tetrachloride to form a free radical"
Reactome:R-HSA-76456 "O-atom dealkylation of dextromethorphan"
Reactome:R-HSA-76466 "CYP4A11 12-hydroxylates DDCX"
Reactome:R-HSA-76472 "Ethylene is oxidized to Ethylene oxide by CYP1A1"
Reactome:R-HSA-76475 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide"
Reactome:R-HSA-8865107 "MICAL1 produces NADP+, H2O2"
Reactome:R-HSA-9018874 "CYP monooxygenates EPA to 18(S)-HpEPE"
Reactome:R-HSA-9027042 "CPY4 -oxidises 14(S)-HDHA to MaR-L1"
Reactome:R-HSA-9027043 "CYPs hydroxylate DHA to 14(R)-HDHA"
Reactome:R-HSA-9027044 "CYP4 -oxidises 14(R)-HDHA to MaR-L2"
Reactome:R-HSA-9027302 "CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA"
Reactome:R-HSA-9027321 "CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA"
Reactome:R-HSA-9037761 "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1"
Reactome:R-HSA-9749986 "CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA"
Reactome:R-HSA-9750016 "CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA"
Reactome:R-HSA-9753285 "CYP2E1 monooxygenates APAP to NAPQI"
Reactome:R-HSA-9756138 "CYP3A4 monooxygenates ATVL to 2-OH-ATVL"
Reactome:R-HSA-9756162 "CYP3A4 monooxygenates ATV to 4-OH-ATV"
Reactome:R-HSA-9756169 "CYP3A4 monooxygenates ATV to 2-OH-ATV"
Reactome:R-HSA-9756180 "CYP3A4 monooxygenates ATVL to 4-OH-ATVL"