General Information
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Term |
RNA polymerase I general transcription initiation factor activity |
ID (Ontology) |
GO:0001181 (Gene Ontology) |
Definition |
A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs.[ PubMed:11500378 PubMed:17972917 PubMed:25346433 PubMed:28340337 PubMed:28842442 PubMed:31358304 ] |
Also Known As |
"general RNA polymerase I transcription factor activity" ; "RNA polymerase I transcription general initiation factor activity" |
Comment |
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Links to Extrernal Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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Data Class | Field | Records |
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Genes (FBgn) | GO_MOLECULAR_FUNCTION | 1 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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Full annotation statements | Relevant FlyBase reports |
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Genes |
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RNA polymerase I general transcription initiation factor activity (all annotations which use CV term, excluding "NOT" statements) | 1 | enables | RNA polymerase I general transcription initiation factor activity | 1 |
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