FB2024_02 , released April 23, 2024
FB2024_02 , released April 23, 2024
CV Term Report
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General Information
Term double-strand break repair via homologous recombination ID (Ontology) GO:0000724 (Gene Ontology)
Definition The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.[ PubMed:10357855 ]
Also Known As "HDR" ; "homologous recombinational repair" ; "homology-directed repair" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      48
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 double-strand break repair via homologous recombination (all annotations which use CV term, excluding "NOT" statements)       1     48
     involved_in | double-strand break repair via homologous recombination       --      48
Spanning Tree (Parents/Children)
Only view relationship: 
DNA repair
 |__recombinational repair______
 |__double-strand break repair__|
DNA recombination               |
 |__recombinational repair______|
                                double-strand break repair via homologous recombination  72 rec.
                                 |__DNA synthesis involved in double-strand break repair via homologous recombination 5 rec.
                                 |__double-strand break repair via break-induced replication 13 rec.
                                 |   |__regulation of double-strand break repair via break-induced replication(+)
                                 |__double-strand break repair via synthesis-dependent strand annealing 11 rec.
                                 |   |__DNA double-strand break processing involved in repair via synthesis-dependent strand annealing
                                 |   |__DNA recombinase assembly(+) 3 rec.
                                 |   |__heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing 1 rec.
                                 |   |__meiotic strand displacement involved in double-strand break repair via SDSA
                                 |__double-strand break repair via transcription-associated homologous recombination
                                 |__regulation of double-strand break repair via homologous recombination 4 rec.
                                 |   |__negative regulation of double-strand break repair via homologous recombination(+)
                                 |   |__positive regulation of double-strand break repair via homologous recombination 1 rec.
                                 |   |__regulation of double-strand break repair via break-induced replication(+)
                                 |__replication-born double-strand break repair via sister chromatid exchange 2 rec.
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Is a recombinational repair
double-strand break repair
Part of
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Synonyms
  • "HDR" EXACT
    "homologous recombinational repair" EXACT
    "homology-directed repair" EXACT
    "HRR" EXACT
    "Rad51-dependent recombinational repair" EXACT
    "Rhp51-dependent recombinational repair" EXACT
Secondary IDs
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