FB2024_04 , released June 25, 2024
FB2024_04 , released June 25, 2024
CV Term Report
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General Information
Term THO complex ID (Ontology) GO:0000347 (Gene Ontology)
Definition The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.[ PubMed:11060033 PubMed:11979277 PubMed:16983072 ]
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
Genes (FBgn)  GO_CELLULAR_COMPONENT       5
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 Genes
 THO complex (all annotations which use CV term, excluding "NOT" statements)       5
     part_of | THO complex       5
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nucleus_____________________
protein-containing complex__|
                            nuclear protein-containing complex
                             |__THO complex  7 rec.
                                 |__nucleoplasmic THO complex 1 rec.
                                 |__THO complex part of transcription export complex 6 rec.
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