A truncated arm protein, lacking amino acids 34 to 87 and tagged with Tag:MYC, is expressed under the control of UASt regulatory sequences. The protein produced is constitutively active in wg signalling, but functions normally at adherens junctions.
report comment: Encodes a modified form of ARM protein with increased stability and altered subcellular distribution: functions normally at adherens junctions, but also accumulates in the cytoplasm and nucleus.
construct_comment: Progenitors are those of the plasmid, pP{UAS-arm.S10}.
report comment: Encodes a modified form of ARM protein with increased stability and altered subcellular distribution: functions normally at adherens junctions, but also accumulates in the cytoplasm and nucleus.