FlyBase Insertion Report: Dmel\P{GawB}insc[Mz1407]

General Information

Symbol

Dmel\P{GawB}insc^Mz1407

Species

D. melanogaster

Name

FlyBase ID

FBti0148948

Feature type

transposable_element_insertion_site

Also Known As

insc-gal4, 1407-Gal4, inscGAL4, inscuteable-Gal4, GAL4-1407, 1407, MZ1407-Gal4, MZ1407, insc-Gal4^MZ1407, Gal4 1407

Description

Inserted Element

P{GawB}

LINE ID

Affected gene(s)

insc, Scer\GAL4

Viability / fertility

viable

Associated allele(s)

insc^Mz1407, Scer\GAL4^insc-Mz1407

Stock availability

2 publicly available

Genomic Location

Chromosomal Location

2R ( 57B3 )

Sequence Location

Target / Docking site

Member of Large Scale Dataset(s)

Dataset

Description

Detailed Mapping Data

Chromosome (arm)

Sequence Location

Orientation

Cytological location (computed by FlyBase)

57B3 (near gene of known cytology)

Cytological location (reported)

Insertion into Natural transposon

Comments concerning location

Sequence Data

Flanking sequence

Inserted Element

Construct

P{GawB}

(FlyBase, 1992-)

Size (Kb)

11.279

Component Allele(s)

Scer\GAL4^wB

w^+mW.hs

Molecular map

Affected Gene(s)

Insertion may affect gene

insc

(Betschinger et al., 2006)

Scer\GAL4

(Sato and Shibuya, 2013, Berger et al., 2012, Moraru et al., 2012, Song and Lu, 2012, Araújo and Casanova, 2011, Ma et al., 2011, Neumüller et al., 2011, Nguyen et al., 2011, Ouyang et al., 2011, Ouyang et al., 2011, Parker et al., 2011, Plyusnina et al., 2011, Viktorin et al., 2011, Wang et al., 2011, Wang et al., 2011, Zhu et al., 2011, Fernandez et al., 2010, Hekmat-Scafe et al., 2010, Lowery et al., 2010, Feiguin et al., 2009, Sousa-Nunes et al., 2009, Wang et al., 2009, Wicker-Thomas et al., 2009, Benetka et al., 2008, Gilestro, 2008, Lindsay et al., 2008, Wirtz-Peitz et al., 2008, Zhu et al., 2008, Dix and Raff, 2007, Joly et al., 2007, Lee et al., 2007, Rusan and Peifer, 2007, Basto et al., 2006, Betschinger et al., 2006, Brankatschk and Dickson, 2006, Hiramoto and Hiromi, 2006, Lind et al., 2006, Morris et al., 2006, Ueno et al., 2006, Verdier et al., 2006, Escudero et al., 2005, Keleman et al., 2005, Albin and Davis, 2004, Lawrence et al., 2004, Lee et al., 2004, Mee et al., 2004, Sprecher et al., 2004, Astle et al., 2003, Kueppers et al., 2003, Missirlis et al., 2003, Page, 2003, Baines et al., 2002, Clark et al., 2002, Lee and Kolodziej, 2002, Page, 2002, Wills et al., 2002, Axelrod, 2001, Fergestad and Broadie, 2001, Kammermeier et al., 2001, Keleman and Dickson, 2001, Llimargas and Lawrence, 2001, Monge et al., 2001, Rusten et al., 2001, Udolph et al., 2001, Yoshida et al., 2001, Estes et al., 2000, Gao et al., 2000, Gatti et al., 2000, Rajagopalan et al., 2000, Rajagopalan et al., 2000, Zars et al., 2000, Usui et al., 1999, Wills et al., 1999, Kaufmann et al., 1998, Prokop et al., 1998, Sanchez Soriano and Russell, 1998, Speicher et al., 1998, Zaffran et al., 1998, Ferveur et al., 1997, Iwai et al., 1997, Lin et al., 1997, Rose et al., 1997, Connolly et al., 1996, Guo et al., 1996, Kolodziej et al., 1996, Broadie et al., 1995, Sweeney et al., 1995, Luo et al., 1994)

Variant Molecular Consequences

Phenotypic Data

Associated Allele

Phenotypic Data

insc^Mz1407

Phenotypic Class Phenotype Manifest in Detailed Description

Scer\GAL4^insc-Mz1407

Phenotypic Class Phenotype Manifest in Detailed Description

Expression Data

Reporter Expression

No Assay Recorded

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 10 -- 12

neuroblast

(Luo et al., 1994)

embryonic stage 13 -- 17

presumptive embryonic/larval nervous system

(Luo et al., 1994)

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

nervous system

(Fergestad and Broadie, 2001)

presumptive embryonic/larval nervous system

(Prokop et al., 1998)

embryonic neuroblast

(Prokop et al., 1998)

second instar larval stage

mushroom body neuroblast

Comment: 36 hours after hatching

(Kraft et al., 2016)

embryonic/larval neuron | subset of embryonic/larval mushroom body

Comment: 36 hours after hatching

(Kraft et al., 2016)

ganglion mother cell of embryonic/larval mushroom body

Comment: 36 hours after hatching

(Kraft et al., 2016)

second instar larval stage -- third instar larval stage

neuroblast of embryonic/larval optic lobe

(Wang et al., 2011)

neuroblast of embryonic/larval brain

(Wang et al., 2011)

neuroblast of larval ventral nerve cord

(Wang et al., 2011)

early third instar larval stage

mushroom body neuroblast

Comment: 48 hours after hatching

(Kraft et al., 2016)

embryonic/larval neuron | subset of embryonic/larval mushroom body

Comment: 48 hours after hatching

(Kraft et al., 2016)

ganglion mother cell of embryonic/larval mushroom body

Comment: 48 hours after hatching

(Kraft et al., 2016)

late third instar larval stage

mushroom body neuroblast

Comment: 96 hours after hatching

(Kraft et al., 2016)

embryonic/larval neuron | subset of embryonic/larval mushroom body

Comment: 96 hours after hatching

(Kraft et al., 2016)

ganglion mother cell of embryonic/larval mushroom body

Comment: 96 hours after hatching

(Kraft et al., 2016)

pharate adult stage P9

mushroom body neuroblast

Comment: 72 hours APF

(Kraft et al., 2016)

Kenyon cell | subset

Comment: 72 hours APF

(Kraft et al., 2016)

ganglion mother cell of adult mushroom body

Comment: 72 hours APF

(Kraft et al., 2016)

adult stage

adult nervous system

(Connolly et al., 1996)

Kenyon cell | subset

(Kraft et al., 2016)

adult oenocyte

(Ferveur et al., 1997)

adult midgut

(Ferveur et al., 1997)

Additional Information

Statement

Reference

Drives expression most segregating embryonic neuroblasts and their progeny, but not in the neurectoderm; in neuroblasts of the larval optic lobe, central brain, and ventral nerve cord, but not the neuroepithelial cells of the outer optic anlage (OPC).

(FlyBase Curators, 2017)

ScerGAL4^insc-Mz1407 drives expression in proximal parts of neuroblast lineages up to and including young Kenyon cells, but not mature Kenyon cells. Expression overlaps with dpn positive mushroom body neuroblasts and Rx positive ganglion mother cells and young Kenyon cells and with dac in some Kenyon cells at the late third instar larval stage.

(Kraft et al., 2016)

ScerGAL4^insc-Mz1407 drives expression in neuroblasts of the larval optic lobe, central brain, and ventral nerve cord, but not the neuroepithelial cells of the outer optic anlage (OPC).

(Wang et al., 2011)

Expression is observed throughout the nervous system during embryogenesis, but ceases after hatching.

(Fergestad and Broadie, 2001)

In embryo, expressed in most segregated neuroblasts and their progeny, but not in the neurectoderm.

(Prokop et al., 1998)

In embryo, expressed in many segregating neuroblasts and their progeny; is not expressed in the ventral midline.

(Sanchez Soriano and Russell, 1998)

Pan-neural expression in the embryo: in all peripheral sensory neurons, cell bodies of the CNS, afferent and efferent axons in the peripheral nerves and in individual boutons of the neuromuscular junction.

(Sweeney et al., 1995)

Marker for

embryonic neuroblast

(Prokop et al., 1998, Sanchez Soriano and Russell, 1998)

presumptive embryonic/larval nervous system

(Fergestad and Broadie, 2001)

Reflects expression of

insc

(Kraft et al., 2016, Wang et al., 2011)

Reporter construct used in assay

N^NIG.3936R

(Wang et al., 2011)

Data on Genetic Line

Line ID

Origin as a multiple insertion line

Progenitor(s) within the Genome

Related Aberration or Balancer

Aberration

Balancer

Stocks (2)

Bloomington

8751

w^*; P{GawB}insc^Mz1407

25773

w^*; P{GawB}insc^Mz1407/CyO; P{UAS-ChRFP-Tub}3

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (57)

Reported As

Symbol Synonym

1407

(Borg et al., 2016, Borg and Cauchi, 2013, Hekmat-Scafe et al., 2010, Morris et al., 2006, Estes et al., 2000)

1407 Gal4

(Gilestro, 2008)

1407-gal4

(Poidevin et al., 2024, Wicker-Thomas et al., 2015, Kohwi et al., 2013, Fernandez et al., 2010)

1407.Gal4

(Lawrence et al., 2004)

1407::Gal4

(Sprecher et al., 2004)

1407>Gal4

(Zhu et al., 2008)

1407Gal4

(Llimargas and Lawrence, 2001)

GAL4-1407

(Kelly et al., 2016, Moskalev et al., 2012, Plyusnina et al., 2011, Axelrod, 2001, Luo et al., 1994)

GAL4¹⁴⁰⁷

(Gold and Brand, 2014)

Gal4 1407

(Kimura et al., 2006, Gao et al., 2000)

Gal4-1407

(Joly et al., 2007, Rusan and Peifer, 2007)

Gal41407

(Morrissy et al., 2016)

GawB1407

(Chen et al., 2015)

Insc-G4

(Loewen et al., 2018)

Insc-GAL4

(Chen et al., 2015, Yuva-Aydemir et al., 2015, Aughey et al., 2014, Gold and Brand, 2014, Sousa-Nunes et al., 2009)

Insc-GAL4^MZ1407

(Díaz-de-la-Peña et al., 2020)

Insc-Gal4

(Mannino et al., 2023, Zhu et al., 2023, Ábrahám et al., 2022, Gallaud et al., 2022, Thomas et al., 2021, Yu et al., 2020, Piggott et al., 2019, Hartenstein et al., 2018, Foo et al., 2017, Lim et al., 2017, Wang et al., 2009)

InscGAL4

(Kasturacharya et al., 2023)

Inscuteable-Gal4

(Shinoda et al., 2023, Thomas et al., 2021)

MZ1407

(Tang et al., 2022, Sousa-Nunes et al., 2009, Dix and Raff, 2007, Basto et al., 2006, Hiramoto and Hiromi, 2006)

MZ1407(insc)-Gal4

(Abramczuk et al., 2017, Berger et al., 2012)

MZ1407-GAL4

(Rusten et al., 2001)

MZ1407-Gal4

(Berger et al., 2012)

Mz1407-GAL4

(Spéder and Brand, 2014)

Mz1407-Gal4

(Kuert et al., 2012, Kunz et al., 2012)

(Wicker-Thomas et al., 2015)

P(GawB)1407

(Moskalev et al., 2012)

P[1407-GAL4]

(Wills et al., 1999)

P[GAL4-1407]

(Usui et al., 1999)

P[Gal4]1407

(Gatti et al., 2000)

P{GAL4-1407}

(Lindsay et al., 2008)

P{GAL4}Mz1407

(Speicher et al., 1998, FlyBase, 1992-)

P{GAL4}oeB

P{GawB}1407

(Ma et al., 2011, FlyBase, 1992-)

P{GawB}insc^MZ1407

(Ding et al., 2016)

P{GawB}insc^Mz1407

(Gil-Ranedo et al., 2019, Zappia and Frolov, 2016)

P{GawB}insc[Mz1407]

(Reitman et al., 2015)

P{w^+mW.hs=GawB}insc^Mz1407

(Shah et al., 2018)

insc-GAL4^Mz1407

(Contreras et al., 2018)

insc-Gal4

(Connell et al., 2024, Muñoz-Oreja et al., 2024, Gui et al., 2023, Gujar et al., 2023, Deng et al., 2022, Ho et al., 2022, Sami et al., 2022, Hatch et al., 2021, Métivier et al., 2021, Pryszlak et al., 2021, Yatsenko et al., 2021, Bonnay et al., 2020, Feng et al., 2020, Francisco et al., 2020, Liu et al., 2020, Ly and Wang, 2020, Bahrampour et al., 2019, Gil-Ranedo et al., 2019, Ly et al., 2019, Mirkovic et al., 2019, Koe et al., 2018, Li et al., 2018, Loewen et al., 2018, Mora et al., 2018, Zülbahar et al., 2018, Abramczuk et al., 2017, Li et al., 2017, Lovick et al., 2017, Ngo et al., 2017, Rohith and Shyamala, 2017, Kraft et al., 2016, Lovick et al., 2016, Morrissy et al., 2016, Zhang et al., 2016, Hartenstein et al., 2015, Huang et al., 2015, Omoto et al., 2015, Weng and Cohen, 2015, Butí et al., 2014, Eroglu et al., 2014, Homem et al., 2014, Kuert et al., 2014, Mauri et al., 2014, Carney et al., 2013, Zhou and Luo, 2013, Berger et al., 2012, Kunz et al., 2012, Moraru et al., 2012, Zhu et al., 2012, Neumüller et al., 2011, Ouyang et al., 2011, Viktorin et al., 2011, Wang et al., 2011, Wang et al., 2011, Zhu et al., 2011)

insc-Gal4^MZ1407

(Viktorin et al., 2011)

insc-gal4

(Endow et al., 2019, Bertet et al., 2014)

insc::Gal4

(Rust et al., 2018)

insc^MZ1407-GAL4

(Otsuki and Brand, 2018)

insc>Gal4

(Wirtz-Peitz et al., 2008)

inscG4

(Ding et al., 2016)

inscGAL4

(Sipani and Joshi, 2022, Bakshi et al., 2020, Ghosh et al., 2019, Khandelwal et al., 2017, Araújo and Casanova, 2011)

inscGAL4^Mz1407

(Harrison et al., 2021)

inscGal4

(Rebelo and Homem, 2023, Zacharioudaki et al., 2016)

inscutable-gal4

(Kohwi et al., 2013)

inscuteable GAL4

(Steffen et al., 2013)

inscuteable-GAL4

(Cheetham and Brand, 2018, Spéder and Brand, 2014)

inscuteable-Gal4

(Poon et al., 2016, Carney et al., 2013, Zhu et al., 2011)

oenocyte-expressed Gal4

(Ferveur et al., 1997)

Name Synonyms

Secondary FlyBase IDs

FBti0002377
FBti0009877
FBti0074351

References (227)

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