FlyBase Insertion Report: Dmel\P{GawB}OK6

General Information

Symbol

Dmel\P{GawB}OK6

Species

D. melanogaster

Name

FlyBase ID

FBti0023258

Feature type

transposable_element_insertion_site

Also Known As

OK6-Gal4, OK6, OK6GAL4, OK6::Gal4, OK-Gal4, OK6 Gal4

Description

Inserted Element

P{GawB}

LINE ID

Affected gene(s)

RapGAP1, Scer\GAL4

Viability / fertility

viable

Associated allele(s)

Scer\GAL4^RapGAP1-OK6

Stock availability

1 publicly available

Genomic Location

Chromosomal Location

2L ( 28B1 )

Sequence Location

2L:7,576,638..7,576,638

Target / Docking site

Genomic Maps

JBrowse

Member of Large Scale Dataset(s)

Dataset

Description

Detailed Mapping Data

Chromosome (arm)

Sequence Location

2L:7,576,638..7,576,638

(Sanyal, 2009)

Orientation

Cytological location (computed by FlyBase)

28B1 (inferred by FlyBase from sequence location)

Cytological location (reported)

Insertion into Natural transposon

Comments concerning location

Insertion location reported at 2L:7576638 in R5 coordinates, 34 bp upstream of the transcription start site of RapGAP1..

(Sanyal, 2009)

Sequence Data

Flanking sequence

Inserted Element

Construct

P{GawB}

Size (Kb)

11.279

Component Allele(s)

Scer\GAL4^wB

w^+mW.hs

Molecular map

Affected Gene(s)

Insertion may affect gene

RapGAP1

(Sanyal, 2009)

Scer\GAL4

(Hossain et al., 2023, Zhao et al., 2015, Kerr et al., 2014, Akerboom et al., 2012, Beck et al., 2012, Chen and Ganetzky, 2012, Nechipurenko and Broihier, 2012, Freeman et al., 2011, Inada et al., 2011, James and Broihier, 2011, Keegan et al., 2011, Liu et al., 2011, Pak et al., 2011, Pilgram et al., 2011, Szul et al., 2011, Tamura et al., 2011, Wang et al., 2011, Bachmann et al., 2010, Ball et al., 2010, Banovic et al., 2010, Chouhan et al., 2010, Hallermann et al., 2010, Higashi-Kovtun et al., 2010, Liu et al., 2010, Owald et al., 2010, Tsurudome et al., 2010, Xiong et al., 2010, Jansen et al., 2009, Merino et al., 2009, Russo et al., 2009, Sanyal, 2009, Wairkar et al., 2009, Cauchi et al., 2008, Caygill and Johnston, 2008, Fradkin et al., 2008, Franciscovich et al., 2008, Ratnaparkhi et al., 2008, Wu et al., 2008, Wu et al., 2008, Wang et al., 2007, Ang et al., 2006, Ataman, 2006, Cerrato et al., 2006, Kittel et al., 2006, Parker et al., 2006, Serpe and O'Connor, 2006, van der Plas et al., 2006, Hekmat-Scafe et al., 2005, Sanchez-Soriano et al., 2005, Babcock et al., 2004, Banerjee et al., 2004, Bogdanik et al., 2004, Franco et al., 2004, Kuppers-Munther et al., 2004, McCabe et al., 2004, Sherwood et al., 2004, Landgraf et al., 2003, Marques et al., 2003, McCabe et al., 2003, Aberle et al., 2002, Marques et al., 2002)

Variant Molecular Consequences

Phenotypic Data

Associated Allele

Phenotypic Data

Scer\GAL4^RapGAP1-OK6

Phenotypic Class Phenotype Manifest in Detailed Description

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

motor neuron

(Landgraf et al., 2003, McCabe et al., 2003)

larval stage

apterous-expressing neuron of the lateral cluster of the thorax Ap4 | subset

(Marques et al., 2003)

motor neuron

(McCabe et al., 2004, Marques et al., 2003, Marques et al., 2002)

larval CCAP A1-A4 EN abdominal neuron

(Veverytsa and Allan, 2011)

larval stage -- pupal stage

tracheal section | restricted

(Aberle et al., 2002)

salivary gland

(Aberle et al., 2002)

wing disc

(Aberle et al., 2002)

motor neuron

(Aberle et al., 2002)

third instar larval stage

larval ventral nerve cord

(Sanyal, 2009)

embryonic/larval brain

(Sanyal, 2009)

motor neuron

(Sanyal, 2009)

embryonic/larval optic lobe

(Sanyal, 2009)

larval RP2 motor neuron

(Sanyal, 2009)

larval DA1 motor neuron

(Sanyal, 2009)

synaptic neuropil

(Sanyal, 2009)

larval A1-7-innervating RP2 motor neuron

(Sanyal, 2009)

motor neuron

Comment: expression assayed in cultured cells

(Kuppers-Munther et al., 2004)

Additional Information

Statement

Reference

Drives expression in motor neurons from late embryogenesis through pupariation; and in a randomly variable manner in larval Tv neurons.

(FlyBase Curators, 2017)

The reporter is expressed in CCAP-EN neurons but not in the CCAP-IN neurons.

(Veverytsa and Allan, 2011)

Expressed is observed in the larval central nervous system but not in body wall sensory neurons. Expressed is found in motor neurons but not in Type II terminals (formed by MNISN-II, MNSNa-II and MNSNb/d-II). Expressed is observed in neurons in the larval brain including the optic lobe and is strong in motor neuron axons and their neuro-muscular synapses.

(Sanyal, 2009)

Expression is observed in only a few processes in cultured motor neurons.

(Kuppers-Munther et al., 2004)

Larval expression observed in motorneurons.

(McCabe et al., 2004)

Expression is observed in some or all Tv neurons in a randomly variable manner.

(Marques et al., 2003)

Expression observed in motor neurons from first larval instar through pupariation.

(Aberle et al., 2002)

Marker for

apterous-expressing neuron of the lateral cluster of the thorax Ap4

(Marques et al., 2003)

embryonic/larval motor neuron

(Marques et al., 2003)

larval CCAP A1-A4 EN abdominal neuron

(Veverytsa and Allan, 2011)

motor neuron

(Kuppers-Munther et al., 2004, McCabe et al., 2004, Landgraf et al., 2003, McCabe et al., 2003, Aberle et al., 2002, Marques et al., 2002)

Reflects expression of

RapGAP1

(Sanyal, 2009)

Reporter construct used in assay

Mmus\Cd8a^UAS.cLa.EGFP

(Sanyal, 2009)

Data on Genetic Line

Line ID

Origin as a multiple insertion line

Progenitor(s) within the Genome

Related Aberration or Balancer

Aberration

Balancer

Stocks (1)

Bloomington

64199

P{GawB}OK6

External Crossreferences and Linkouts ( 0 )

Comments

Insertion 34bp upstream of the Rapgap1 transcription start site (at position 7576638 of scaffold AE014134, genome release r5.13).

(Sanyal, 2009)

The orientation of the insertion was not reported.

(Sanyal, 2009)

Synonyms and Secondary IDs (25)

Reported As

Symbol Synonym

Gal4-OK6

(Bachmann et al., 2010)

OK-6 GAL4

(Wairkar et al., 2009)

OK-Gal4

(van der Plas et al., 2006)

OK6

(Jetti et al., 2023, Muhammad et al., 2015, Barclay et al., 2014, Rusan et al., 2014, Borg and Cauchi, 2013, Fujita et al., 2013, Macleod et al., 2013, Yamanaka et al., 2013, Freeman et al., 2011, Keegan et al., 2011, Tsurudome et al., 2010, Merino et al., 2009, Sanyal, 2009, Sun et al., 2009, Cerrato et al., 2006, McCabe et al., 2003)

OK6 > Gal4

(Banerjee et al., 2021)

OK6 GAL4

(Faust et al., 2014)

OK6 Gal4

(Smith et al., 2012)

OK6-GAL4

(Lee et al., 2024, Bennett et al., 2023, He et al., 2023, Herrera and Cauchi, 2023, Justs et al., 2023, Lei et al., 2023, Byrne et al., 2022, Han et al., 2022, Wang et al., 2022, Kim et al., 2021, Kirk et al., 2021, Krick et al., 2021, Basargekar et al., 2020, Fowler et al., 2020, He et al., 2020, McNeill et al., 2020, Meloni et al., 2020, Odierna et al., 2020, Wei et al., 2020, Jantrapirom et al., 2019, Lembke et al., 2019, Politano et al., 2019, Zhang et al., 2019, Bulgari et al., 2018, Kim et al., 2018, Straub et al., 2018, Vukoja et al., 2018, Aguilar et al., 2017, Byrne et al., 2017, Hosaka et al., 2017, Inoshita et al., 2017, Kuklin et al., 2017, Lanfranco et al., 2017, Lembke et al., 2017, Makhijani et al., 2017, Matsunaga et al., 2017, Backhaus et al., 2016, Borg et al., 2016, Fowler and O'Sullivan, 2016, Krill and Dawson-Scully, 2016, Deivasigamani et al., 2015, Kroll et al., 2015, Schachtner et al., 2015, Barclay et al., 2014, Kohsaka et al., 2014, McDermott et al., 2014, Roy and Jackson, 2014, Yun et al., 2014, Borg and Cauchi, 2013, Yu et al., 2013, Yu et al., 2013, Zhu et al., 2013, Chouhan et al., 2012, Olesnicky et al., 2012, Wang et al., 2012, Pilgram et al., 2011, Veverytsa and Allan, 2011, Chouhan et al., 2010, Jansen et al., 2009, Menon et al., 2009, Cauchi et al., 2008, Franciscovich et al., 2008, Ratnaparkhi et al., 2008, Wang et al., 2007, Hekmat-Scafe et al., 2005, Bogdanik et al., 2004, McCabe et al., 2004, Sherwood et al., 2004, Suster et al., 2004)

OK6-Gal4

(Gao et al., 2024, Bazzi et al., 2023, Hossain et al., 2023, Nemtsova et al., 2023, Zhou et al., 2023, Hanson and Lemaitre, 2022, Saunders et al., 2022, Tendulkar et al., 2022, Belalcazar et al., 2021, Bhat et al., 2021, Giachello et al., 2021, Lund et al., 2021, Chakraborty et al., 2020, Fort-Aznar et al., 2020, González-Gutiérrez et al., 2020, Han et al., 2020, Kiragasi et al., 2020, Lu et al., 2020, West et al., 2020, Yuan et al., 2020, Zhao et al., 2020, Held et al., 2019, Kamimura et al., 2019, Kikuma et al., 2019, Zhao et al., 2019, Azpurua et al., 2018, Beck et al., 2018, Huang et al., 2018, Molnar et al., 2018, Talmat-Amar et al., 2018, Uechi et al., 2018, West et al., 2018, Xing et al., 2018, Bruckner et al., 2017, Casas-Tintó et al., 2017, Chen et al., 2017, Devambez et al., 2017, Kikuma et al., 2017, Kiragasi et al., 2017, Kreko-Pierce and Eaton, 2017, Li et al., 2017, Zhang et al., 2017, Zhang et al., 2017, Clark et al., 2016, Duan et al., 2016, Hao et al., 2016, Huang et al., 2016, Li et al., 2016, Sakuma et al., 2016, Slabbaert et al., 2016, Summerville et al., 2016, Ziegler et al., 2016, Siebert et al., 2015, West et al., 2015, Zhao et al., 2015, Barclay et al., 2014, Brace et al., 2014, Choi et al., 2014, Dodson et al., 2014, Kerr et al., 2014, Li et al., 2014, Liu et al., 2014, Shiraishi et al., 2014, Xing et al., 2014, Arribat et al., 2013, Chang et al., 2013, Forrest et al., 2013, Fujita et al., 2013, Klinedinst et al., 2013, Korkut et al., 2013, Akerboom et al., 2012, Beck et al., 2012, Chen and Ganetzky, 2012, Dahlgaard et al., 2012, Imlach et al., 2012, Li et al., 2012, Rawson et al., 2012, Inada et al., 2011, Liu et al., 2011, Pak et al., 2011, Talmat-Amar et al., 2011, Tamura et al., 2011, Wang et al., 2011, Ball et al., 2010, Banovic et al., 2010, Chouhan et al., 2010, Ellis et al., 2010, Higashi-Kovtun et al., 2010, Liu et al., 2010, Xiong et al., 2010, Lee and Lundell, 2007, Xiao et al., 2007, Ang et al., 2006, Ataman, 2006, Parker et al., 2006, Serpe and O'Connor, 2006, Sanchez-Soriano et al., 2005, Franco et al., 2004, Kuppers-Munther et al., 2004, Landgraf et al., 2003, Aberle et al., 2002, Marques et al., 2002)

OK6-gal4

(Vuilleumier et al., 2022, Wang et al., 2018, Wu et al., 2008, Wu et al., 2008)

OK6::Gal4

(Rossano et al., 2013, Russo et al., 2009)

OK6:GAL4

(Ivannikov and Macleod, 2013)

OK6GAL4

(O'Sullivan et al., 2012, Banerjee et al., 2004)

OK6Gal4

(Titus et al., 2021, Nechipurenko and Broihier, 2012, James and Broihier, 2011, Caygill and Johnston, 2008)

Ok-GAL4

(Fradkin et al., 2008)

Ok6

(Moss-Taylor et al., 2019)

Ok6-GAL4

(Kobbersmed et al., 2020, Reddy-Alla et al., 2017, Böhme et al., 2016, Li et al., 2015, Babcock et al., 2004)

Ok6-Gal4

(Velten et al., 2022, Ramesh et al., 2021, Kim and Cho, 2020, Neisch et al., 2017, Babic et al., 2015, Chang et al., 2015, Shi et al., 2013)

P(Gal4)OK6

(Coombes et al., 2020)

P<up>w+, OK6::Gal4</up>

(Chouhan et al., 2010)

P{GawB}OK6

(Zhao et al., 2019, Szul et al., 2011, Kuppers-Munther et al., 2004, McCabe et al., 2004, Marques et al., 2003, McCabe et al., 2003, Aberle et al., 2002, Marques et al., 2002, FlyBase, 1992-)

ok6

(Rui et al., 2017)

ok6-GAL4

(Scholz et al., 2023, Paul et al., 2022, Yang et al., 2021, Scholz et al., 2019, Scholz et al., 2017, Scholz et al., 2015, Dawydow et al., 2014, Podufall et al., 2014, Hallermann et al., 2010, Owald et al., 2010, Kittel et al., 2006)

ok6-Gal4

(Petzoldt et al., 2020, Zala et al., 2013, Owald et al., 2012)

ok6-gal4

(Xu et al., 2023, Shakiryanova et al., 2011, Schmid et al., 2008, Schmid et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (240)

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