Fernando Vazquez, J., Perez, T., Albornoz, J., Dominguez, A. (2000). Estimation of microsatellite mutation rates in Drosophila melanogaster.  Genet. Res. (Camb.) 76(3): 323--326.

FBrf0134642

Research paper

Microsatellite mutations were studied in a set of 175 mutation accumulation lines, all of them independently derived from a completely homozygous population of Drosophila melanogaster and maintained under strong inbreeding during 80 generations. We assayed 28 microsatellites and detected two mutations. One mutation consisted of a single addition of a dinucleotide repeat and the other was a deletion of five trinucleotide repeats. The average mutation rate was 5.1 x 10(-6), in full agreement with previous estimates from two different sets of mutation accumulation lines.