Horowitz, D.S., Krainer, A.R. (1994). Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing.  Trends Genet. 10(3): 100--106.

FBrf0089953

Review

Identification of 5' splice sites requires that limited and dispersed sequence information be interpreted precisely. Both snRNAs and proteins are required for this process. The selection of 5' splice sites in alternative splicing is closely related to that in constitutive splicing, and uses the same components in somewhat different ways.