FlyBase Gene Report: Dmel\siRNA

General Information

Symbol

Dmel\siRNA

Species

D. melanogaster

Name

Annotation Symbol

Feature Type

gene_group

FlyBase ID

FBgn0283511

Gene Model Status

Unannotated

Stock Availability

None publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Function

Gene Ontology (GO) Annotations (0 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Sequence Ontology: Class of Gene

gene_group

(Elbashir et al., 2001)

Transcript Data

Annotated Transcripts

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Polypeptides with Identical Sequences

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\siRNA using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

NA

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\siRNA in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\siRNA

View exonic expression by tissue for Dmel\siRNA

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of siRNA

Transgenic constructs containing regulatory region of siRNA

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (0)

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (0)

Mus musculus (laboratory mouse) (0)

Xenopus tropicalis (Western clawed frog) (0)

Danio rerio (Zebrafish) (0)

Caenorhabditis elegans (Nematode, roundworm) (0)

Anopheles gambiae (African malaria mosquito) (0)

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:siRNA. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Other Interaction Browsers

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

Cytogenetic map

Sequence location

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (0)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

siRNA

(Kingston and Bartel, 2021, Lauria Sneideman and Meller, 2021, Luo et al., 2020, Besnard-Guérin et al., 2015, Chak et al., 2015, Feltzin et al., 2015, Iwasaki et al., 2015, Jimenez-Sanchez et al., 2015, Webster et al., 2015, Wen et al., 2015, Yao et al., 2015, Bronkhorst et al., 2014, Deshpande and Meller, 2014, Dueck and Meister, 2014, Elmer et al., 2014, Fukunaga and Zamore, 2014, Han and Zamore, 2014, Lim et al., 2014, Lim et al., 2014, Matts et al., 2014, Menon et al., 2014, Mirkovic-Hösle and Förstemann, 2014, Pandey et al., 2014, Piatek and Werner, 2014, Shpiz et al., 2014, Wakiyama and Yokoyama, 2014, Wang et al., 2014, Wang et al., 2014, Wen et al., 2014, Yang and Pillai, 2014, Yilmazel et al., 2014, Yun and Dasgupta, 2014, Barckmann and Simonelig, 2013, Benosman et al., 2013, Carré et al., 2013, Castel and Martienssen, 2013, Durdevic et al., 2013, Flores-Jasso et al., 2013, Ge and Zamore, 2013, Gomes et al., 2013, Hur et al., 2013, Knævelsrud et al., 2013, Lim et al., 2013, Marques et al., 2013, Meister, 2013, Nalavade et al., 2013, Nishida et al., 2013, Rozhkov et al., 2013, Sabin et al., 2013, Xie et al., 2013, Xiong et al., 2013, Yamanaka et al., 2013, Zhang et al., 2013, Backes et al., 2012, Dahal et al., 2012, de Vanssay et al., 2012, Fukunaga et al., 2012, Hedges et al., 2012, Helfer et al., 2012, Ji and Chen, 2012, Marco, 2012, Menon and Meller, 2012, Nesic et al., 2012, Paro et al., 2012, Qi et al., 2012, Wee et al., 2012, Zhang et al., 2012, Ameres et al., 2011, Antoniewski, 2011, Betanska et al., 2011, Birchler and Xie, 2011, Cenik et al., 2011, Ding and Lu, 2011, Gerbasi et al., 2011, Han et al., 2011, Harris et al., 2011, Hartig and Förstemann, 2011, Kawamata and Tomari, 2011, Lim et al., 2011, Liu et al., 2011, Maiti et al., 2011, Meng et al., 2011, Moshkovich et al., 2011, Nayak and Andino, 2011, Okamura et al., 2011, Pek and Kai, 2011, Qi et al., 2011, Qin et al., 2011, Rozhkov et al., 2011, Shih and Hunter, 2011, Tamura et al., 2011, Tchurikov and Kretova, 2011, Tian et al., 2011, van Mierlo et al., 2011, Welker et al., 2011, Xie et al., 2011, Yang and Li, 2011, Yu et al., 2011, Ameres et al., 2010, Bartkowiak et al., 2010, Förstemann, 2010, Gerbasi et al., 2010, Ghildiyal et al., 2010, Hain et al., 2010, Haley et al., 2010, Iwasaki et al., 2010, Jung et al., 2010, Lipardi and Paterson, 2010, Liu and Paroo, 2010, Marques et al., 2010, Miller et al., 2010, Miyoshi et al., 2010, Miyoshi et al., 2010, Moshkovich and Lei, 2010, Mukherjee and Hanley, 2010, Riedmann and Schwentner, 2010, Rozhkov et al., 2010, Shi et al., 2010, White et al., 2010, Wu et al., 2010, Berry et al., 2009, Czech et al., 2009, Fagegaltier et al., 2009, Flynt et al., 2009, Hartig et al., 2009, Heale et al., 2009, Hirst et al., 2009, James et al., 2009, Kotelnikov et al., 2009, Lau et al., 2009, Lee et al., 2009, Lipardi and Paterson, 2009, Lucchetta et al., 2009, Morciano et al., 2009, Pepper et al., 2009, Sabin et al., 2009, Singh et al., 2009, Thomson and Lin, 2009, Tomari, 2009, van Rij and Berezikov, 2009, Venkiteswaran and Hasan, 2009, Verdel et al., 2009, Zhou et al., 2009, Zhou et al., 2009, Aliyari et al., 2008, Berry et al., 2008, Chung et al., 2008, Conti and Adelstein, 2008, Deddouche et al., 2008, Emberly et al., 2008, Ghildiyal et al., 2008, Golden et al., 2008, Horabin and Olcese, 2008, Kalidas et al., 2008, Kavi and Birchler, 2008, Korbut et al., 2008, Lakatos and Burgyán, 2008, Lim et al., 2008, Liu et al., 2008, Melani et al., 2008, Misquitta et al., 2008, Miyoshi et al., 2008, Obbard and Finnegan, 2008, Okamura and Lai, 2008, Okamura et al., 2008, Okamura et al., 2008, Okamura et al., 2008, Ronsseray et al., 2008, Rudnick et al., 2008, Seinen and Sibon, 2008, Shpiz et al., 2008, Tang et al., 2008, Wu and Belasco, 2008, Ye and Liu, 2008, Yi et al., 2008, Zhou et al., 2008, Anonymous, 2007, Antoniewski et al., 2007, Berry et al., 2007, Bhadra et al., 2007, Blumenstiel et al., 2007, Chen et al., 2007, Eleftherianos et al., 2007, Förstemann et al., 2007, Galiana-Arnoux et al., 2007, Glaser et al., 2007, Gunawardane et al., 2007, Hartig et al., 2007, Horn et al., 2007, Horn et al., 2007, Horwich et al., 2007, Josse et al., 2007, Kavi and Birchler, 2007, Kim et al., 2007, Klattenhoff et al., 2007, Klattenhoff et al., 2007, Klenov et al., 2007, Lavrov and Kibanov, 2007, Liu et al., 2007, Moffat et al., 2007, Pelisson et al., 2007, Perrimon and Mathey-Prevot, 2007, Peters and Meister, 2007, Petruk et al., 2007, Ronsseray et al., 2007, Seinen and Sibon, 2007, Sharma and Nirenberg, 2007, Tchurikov and Kretova, 2007, Tomari et al., 2007, Ueda et al., 2007, Baqri et al., 2006, Bhadra et al., 2006, Dorner et al., 2006, Du et al., 2006, Kim et al., 2006, Liu et al., 2006, Megosh et al., 2006, Meyer et al., 2006, Nishida and Siomi, 2006, Petruk et al., 2006, Preall et al., 2006, Saito et al., 2006, Usakin et al., 2006, Vagin et al., 2006, Vagin et al., 2006, Valencia-Sanchez et al., 2006, Wakiyama et al., 2006, Yang and Wu, 2006, Zambon et al., 2006, Blumenstiel and Hartl, 2005, Blumenstiel and Hartl, 2005, Jiang et al., 2005, Kalidas et al., 2005, Kavi et al., 2005, Lipardi et al., 2005, Matranga et al., 2005, Miyoshi et al., 2005, Pham and Sontheimer, 2005, Preall and Sontheimer, 2005, Rand et al., 2005, Siomi et al., 2005, Sontheimer and Carthew, 2005, Tang, 2005, Tu and Akgul, 2005, Wakiyama et al., 2005, Wu et al., 2005, Blumenstiel and Hartl, 2004, Buckingham et al., 2004, Caudy and Hannon, 2004, Haley and Zamore, 2004, Hall, 2004, Hutvagner et al., 2004, Kawasaki et al., 2004, Lakatos et al., 2004, Lee et al., 2004, Lingel et al., 2004, Nakahara and Carthew, 2004, Okamura et al., 2004, Pham et al., 2004, Robert and Bucheton, 2004, Schwarz et al., 2004, Siomi et al., 2004, Snove et al., 2004, Tijsterman and Plasterk, 2004, Tomari et al., 2004, Tomari et al., 2004, Ui-Tei et al., 2004, Unwalla et al., 2004, Verma and Dey, 2004, Boutla et al., 2003, Churikov and Kretova, 2003, Goolsby and Shapiro, 2003, Gvozdev et al., 2003, Haley et al., 2003, Khvorova et al., 2003, Klenov et al., 2003, Lingel et al., 2003, Liu et al., 2003, Ono et al., 2003, Roignant et al., 2003, Schwarz et al., 2003, Silverstein and Mumby, 2003, Sledz et al., 2003, Song et al., 2003, Wei et al., 2003, Zeng et al., 2003, Hutvagner and Zamore, 2002, Ramaswamy and Slack, 2002, Schwarz et al., 2002, Williams and Rubin, 2002, Yang et al., 2002, Boutla et al., 2001, Elbashir et al., 2001, Elbashir et al., 2001, Elbashir et al., 2001, Lipardi et al., 2001, Nishikura, 2001, Nykanen et al., 2001, Scadden and Smith, 2001)

Name Synonyms

short interfering RNA

(Elbashir et al., 2001)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 0 )

References (299)

NA

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