FB2024_02 , released April 23, 2024
Gene Group: KMN PROTEIN NETWORK
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General Information
Name
KMN PROTEIN NETWORK
Species
D. melanogaster
Symbol
KMN
FlyBase ID
FBgg0001871
Date last reviewed
2023-11-08
Number of members
8
Description
Description
The KMN protein network is a supercomplex of the kinechore composed of the KNL1, Mis12 and Ndc80 complexes. During chromosome segregation during mitosis and meiosis, the KMN connects spindle microtubules and centromeres. (Adapted from FBrf0231099 and FBrf0231098.)
Notes on Group
Source Material
The KMN PROTEIN NETWORK Gene Group has been compiled using the following publication(s): Richter et al., 2016 and Schittenhelm et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
kinetochore
Related Gene Groups
Component group(s)
KINETOCHORE MIS12 COMPLEX - NF1A VARIANT
KINETOCHORE MIS12 COMPLEX - NF1B VARIANT
KNL1 SUBUNIT
NDC80 KINETOCHORE COMPLEX
Members (8)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
KINETOCHORE MIS12 COMPLEX - NF1A VARIANT
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Kmn1
kinetochore Mis12-Ndc80 network component 1
Nsl1, l(1)G0237
(Richter et al., 2016, Schittenhelm et al., 2007)
Mis12
Mis12
dmMis12
(Richter et al., 2016, Schittenhelm et al., 2007)
Nnf1a
Nnf1a
(Richter et al., 2016, Schittenhelm et al., 2007)
KINETOCHORE MIS12 COMPLEX - NF1B VARIANT
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Kmn1
kinetochore Mis12-Ndc80 network component 1
Nsl1, l(1)G0237
(Schittenhelm et al., 2007)
Mis12
Mis12
dmMis12
(Schittenhelm et al., 2007)
Nnf1b
Nnf1b
(Schittenhelm et al., 2007)
KNL1 SUBUNIT
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Spc105R
Spc105-related
Spc105, KNL1
(Schittenhelm et al., 2007)
NDC80 KINETOCHORE COMPLEX
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Ndc80
Ndc80
Hec1, dmNdc80
(Schittenhelm et al., 2007)
Nuf2
Nuf2
(Schittenhelm et al., 2007)
Spc25
Spc25
Mitch, BcDNA:LD37196, l(3)S3, chromosome alignment defect 2, l(3)87Da
(Schittenhelm et al., 2007)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
KMN
KMN network
Knl1 complex, Mis12 complex, Ndc80 complex network
KNL1, MIS12, NDC80 network
KMN PROTEIN NETWORK
Secondary FlyBase ID(s)
References (3)