Gene Group - Pathway: Torso Signaling Pathway

General Information

Name

Torso Signaling Pathway

Species

D. melanogaster

Symbol

TORS

FlyBase ID

FBgg0000934

Date last reviewed

2018-06-19

Number of members

Description

The Torso signaling pathway is best characterized in the formation of Drosophila embryonic termini, controlled by the localized activation of Torso (tor) receptor tyrosine kinase by trk. Torso signaling has also been shown to regulate larval processes via Ptth activation of tor. The Torso signaling pathway acts via the canonical Ras/Raf/MAP kinase cascade. (Adapted from FBrf0157176 and FBrf0242089.)

Notes and selected reviews

Selected publications for background information: Functions and mechanisms of receptor tyrosine kinase Torso signaling:lessons from Drosophila embryonic terminal development (FBrf0183895), In and out of Torso RTK signalling (FBrf0157176), Dissection of the torso signal transduction pathway in Drosophila (FBrf0085737), Receptor tyrosine kinases in Drosophila development (FBrf0221727).

Note: Pathway Pages in FlyBase are under development. The pathway gene tables display genes that have been experimentally shown to act within the pathway or modify pathway activity. We welcome any feedback to help improve the usefulness and accuracy of these gene lists.

Biological Process Gene Ontology (GO) term(s)

Related Gene Groups

Component group(s)

Negative Regulators of Torso Signaling Pathway

Positive Regulators of Torso Signaling Pathway

Torso Signaling Pathway Core Components

Physical Interaction Network

Members (31)

For all members: