FB2024_03 , released June 25, 2024
Gene Group: PROTEIN DISULFIDE ISOMERASES
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General Information
Name
PROTEIN DISULFIDE ISOMERASES
Species
D. melanogaster
Symbol
PDI
FlyBase ID
FBgg0000821
Date last reviewed
2019-11-08
Number of members
13
Description
Description
Protein disulfide isomerases catalyze disulfide bond formation (oxidase activity) and the rearrangement of incorrect disulfides (isomerase activity). They function as chaperones within the endoplasmic reticulum to ensure the correct folding of secreted/cell surface proteins during their maturation. (Adapted from PMID:15158710.)
Notes on Group
Source Material
Key Gene Ontology (GO) terms
Molecular Function
protein disulfide isomerase activity
Biological Process
protein folding
Cellular Component
endoplasmic reticulum
Enzymatic activity
Enzyme name (EC)
protein disulfide-isomerase (5.3.4.1)
Related Gene Groups
Parent group(s)
INTRAMOLECULAR OXIDOREDUCTASES
Members (13)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CaBP1
calcium-binding protein 1
BG:DS09218.4, DmCaBP1, AAL28897
(FlyBase, 2017-)
CG9302
(FlyBase, 2017-)
CG10029
(FlyBase, 2017-)
CG10948
(FlyBase, 2017-)
CG18132
(FlyBase, 2017-)
ERp44
Endoplasmic reticulum protein 44
(FlyBase, 2017-)
ERp60
Endoplasmic reticulum p60
D-ERp60
(FlyBase, 2017-)
Pdi
Protein disulfide isomerase
dpdi, l(3)j2A2
(FlyBase, 2017-)
prtp
pretaporter
p47
(FlyBase, 2017-)
Qsox1
Quiescin sulfhydryl oxidase 1
lincRNA.300
(FlyBase, 2017-)
Qsox2
Quiescin sulfhydryl oxidase 2
(FlyBase, 2017-)
Qsox3
Quiescin sulfhydryl oxidase 3
(FlyBase, 2017-)
Qsox4
Quiescin sulfhydryl oxidase 4
(FlyBase, 2017-)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
Intramolecular isomerases transposing S-S bonds
INTRAMOLECULAR OXIDOREDUCTASES TRANSPOSING S-S BONDS
INTOS
PROTEIN DISULFIDE ISOMERASES
PDI
Secondary FlyBase ID(s)
References (2)