FB2024_04 , released June 25, 2024
Gene Group: SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS
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General Information
Name
SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS
Species
D. melanogaster
Symbol
SIX
FlyBase ID
FBgg0000751
Date last reviewed
2017-07-27
Number of members
3
Description
Description
Sine oculis homeobox (SIX) transcription factors are sequence-specific DNA binding proteins that regulate transcription and play important role in development. They are characterized by 120 amino acid SIX-type DNA-binding domain N-terminal to a homeodomain. (Adapted from FBrf0232555, FBrf0128773 and PMID:18797923).
Notes on Group
Source Material
The SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS Gene Group has been compiled using the following publication(s): Bürglin and Affolter, 2016, Zhong and Holland, 2010, and Kawakami et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-binding transcription factor activity
transcription cis-regulatory region binding
Biological Process
regulation of DNA-templated transcription
Cellular Component
nucleus
Related Gene Groups
Parent group(s)
HOMEOBOX TRANSCRIPTION FACTORS
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Optix
Optix
opt, Six3, Dsix3, D-Six3
(Bürglin and Affolter, 2016, Zhong and Holland, 2010, Kawakami et al., 2000)
Six4
Six4
DSix4, D-Six4
(Bürglin and Affolter, 2016, Zhong and Holland, 2010, Kawakami et al., 2000)
so
sine oculis
Drl, mda, medusa
(Bürglin and Affolter, 2016, Zhong and Holland, 2010, Kawakami et al., 2000)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SIX
SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS
SINE homeobox family
SINE
Secondary FlyBase ID(s)
References (4)