FB2024_04 , released June 25, 2024
Gene Group: SERINE-ARGININE PROTEIN KINASES
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General Information
Name
SERINE-ARGININE PROTEIN KINASES
Species
D. melanogaster
Symbol
SRPK
FlyBase ID
FBgg0000235
Date last reviewed
2015-03-25
Number of members
3
Description
Description
Serine-arginine protein kinases (SRPKs) are a group of serine kinases that phosphorylate proteins with serine-arginine dipeptide repeats, particularly targeting the SR family of splicing factors. SRPKs are constitutively active. They contain a well-conserved kinase domain that is bifurcated by a large non-conserved insert domain. (Adapted from PMID:21205204).
Notes on Group
Source Material
The SERINE-ARGININE PROTEIN KINASES Gene Group has been compiled using the following publication(s): Sopko et al., 2014, Manning et al., 2002, Allemand et al., 2001, and Morrison et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
protein serine/threonine kinase activity
Biological Process
protein phosphorylation
Cellular Component
Enzymatic activity
Enzyme name (EC)
non-specific serine/threonine protein kinase (2.7.11.1)
Related Gene Groups
Parent group(s)
CMGC KINASES
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG8565
(Sopko et al., 2014, Manning et al., 2002, Allemand et al., 2001, Morrison et al., 2000)
SRPK
SR Protein Kinase
mat(2)synPL63, fs(2)abc, dSRPK1
(Sopko et al., 2014, Manning et al., 2002, Allemand et al., 2001)
Srpk79D
Serine-arginine protein kinase at 79D
BEST:CK01209
(Sopko et al., 2014, Manning et al., 2002, Allemand et al., 2001, Morrison et al., 2000)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SRPK
SERINE-ARGININE PROTEIN KINASES
SR protein kinases
Serine/arginine-rich splicing factor kinases
SFRS protein kinases
Secondary FlyBase ID(s)
References (5)