FB2024_03 , released June 25, 2024
Gene Group: STE7 MAP KINASE KINASES
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General Information
Name
STE7 MAP KINASE KINASES
Species
D. melanogaster
Symbol
STE7-MAPKK
FlyBase ID
FBgg0000227
Date last reviewed
2015-03-25
Number of members
4
Description
Description
STE7 MAP kinase kinases (MAPKKs) belong to the STE7 subfamily and are serine/threonine kinases that phosphorylate MAP kinases in MAPK signalling cascades. MAPKKs are activated by MAP kinase kinase kinases (MAPKKKs). (Adapted from FBrf0225276.)
Notes on Group
Source Material
The STE7 MAP KINASE KINASES Gene Group has been compiled using the following publication(s): Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000, and Han et al., 1998 .
Key Gene Ontology (GO) terms
Molecular Function
MAP kinase kinase activity
Biological Process
protein phosphorylation
MAPK cascade
Cellular Component
Enzymatic activity
Enzyme name (EC)
mitogen-activated protein kinase kinase (2.7.12.2)
Related Gene Groups
Parent group(s)
STE KINASES
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Dsor1
Downstream of raf1
MEK, Dsor, MAPKK, D-mek, DRODSOR1
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000, Han et al., 1998)
hep
hemipterous
JNKK, MKK7, hp, hem, l(1)G0107
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000, Han et al., 1998)
lic
licorne
MKK3, DMEK3, D-MKK3, p38, DMKK3
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000, Han et al., 1998)
Mkk4
MAP kinase kinase 4
dMKK4, D-MKK4, JNKK2, SEK1/MKK4
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000, Han et al., 1998)
External Data
Synonyms and Secondary IDs
Synonym(s)
STE7-MAPKK
Mitogen-activated protein kinase kinases
STE7 kinases
MAP kinase kinase
Mitogen/Extracellular signal-regulated kinases
STE7
MAP2K
MEK
MKK
MAPKK
STE7 MAP KINASE KINASES
STE7 KINASES (MAPK KINASES)
Secondary FlyBase ID(s)
References (5)