FB2024_04 , released June 25, 2024
Gene Group: CK1 KINASES
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General Information
Name
CK1 KINASES
Species
D. melanogaster
Symbol
CKI
FlyBase ID
FBgg0000222
Date last reviewed
2022-09-05
Number of members
10
Description
Description
The CK1 kinases (Casein Kinase 1 family) share a highly conserved kinase domain. CK1 kinases are serine/threonine kinases with a preference for acidic substrates. The highly variable C-terminal domains are involved in regulating subcellular localization and activity. (Adapted from FBrf0132098, PMID:24825444 and PMID:15722192).
Notes on Group

Casein is not the physiological substrate for this family (PMID:24825444).

Source Material
The CK1 KINASES Gene Group has been compiled using the following publication(s): Sopko et al., 2014, Manning et al., 2002, and Morrison et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
protein serine/threonine kinase activity
Biological Process
protein phosphorylation
Cellular Component
Enzymatic activity
Enzyme name (EC)
non-specific serine/threonine protein kinase (2.7.11.1)
Related Gene Groups
Parent group(s)
PROTEIN KINASES
Members (10)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Asator
Asator
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
ball
ballchen
nhk-1, BcDNA:LD09009, NHK1, nucleosomal histone kinase-1, trip
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
bsd
back seat driver
BcDNA:LD23371
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
CG2577
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
CG7094
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
CG9962
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
CG12147
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
CkIα
Casein kinase Iα
CK1, CK1α, CKI, CK I, Casein Kinase 1
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
dco
discs overgrown
dbt, doubletime, double-time, CKIε, CK1ε
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
gish
gilgamesh
Spider, ms(3)89B, CKIγ, Hrr25, CK1γ
(Sopko et al., 2014, Manning et al., 2002, Morrison et al., 2000)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
CKI
Casein Kinase 1 family
Cell Kinase 1 family
CK1
CK1 KINASES
CASEIN KINASE I FAMILY
Secondary FlyBase ID(s)
References (4)