FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term cold sensitive hypomorphic allele - genetic evidence ID (Ontology) FBcv:0000755 (FlyBase CV)
Definition An allele inferred from genetic evidence to have normal activity at high temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at lower temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).[ FlyBase:FBrf0002371 FlyBase:FBrf0049147 ]
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Data Class Field Records
Alleles (FBal)  ALLELE_CLASS       6
Alleles (FBal)  PROMOTED_CLASS       5
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 Alleles
 cold sensitive hypomorphic allele - genetic evidence (all annotations which use CV term, excluding "NOT" statements)       6
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hypomorphic allele - genetic evidence
 |__temperature conditional hypomorphic allele - genetic evidence__
cold sensitive loss of function allele                             |
 |__cold sensitive hypomorphic allele______________________________|
temperature conditional hypomorphic allele                         |
 |__cold sensitive hypomorphic allele______________________________|
 |__temperature conditional hypomorphic allele - genetic evidence__|
                                                                   cold sensitive hypomorphic allele - genetic evidence  6 rec.
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Is a cold sensitive hypomorphic allele
temperature conditional hypomorphic allele - genetic evidence
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