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General Information
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| Term |
lamina wide-field 1 neuron |
ID (Ontology) |
FBbt:00003741 (Fly Anatomy) |
| Definition |
An intrinsic columnar neuron of the visual system whose cell body is located in the medulla cortex and that has a main projection that ascends via the first optic chiasm into the lamina where it is restricted to a single column for most of its length before making wide-field arborizations in the distal lamina. These neurons also arborize on the distal surface of the medulla in a circular field of about 20 columns. Several linking fibers from this arborization descend into M4 where they form a wide arborization field covering about 30-40 columns (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In the lamina, it forms numerous presynaptic connections to lamina monopolar neuron L3 and lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011). These neurons along with the lamina wide-field 2 neurons express the transcription factor Fer2 (Ozel et al., 2021). They are cholinergic (Davis et al., 2020).[ FlyBase:FBrf0049410 FlyBase:FBrf0204652 FlyBase:FBrf0216925 FlyBase:FBrf0244935 FlyBase:FBrf0247762 ] |
| Also Known As |
"Lawf" ; "LaWF1" ; "Lawf1" |
| Comment |
Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P\{UAS-HA-syt\} - FBtp0015803). The identification of dendrites and axons was done using a UAS-Dscam (P\{UAS-Dscam.exon17.1.GFP\} - FBtp0021447) or a UAS-tau (P\{UAS-tau-lacZ.O\} - FBtp0010033) reporter, respectively (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lawf (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (1/1), R2 (3/-), R3 (1/-), R6 (1/-), L1 (1/-), L2 (7/-), L3 (17/-), L5 (1/-), Lai (24/-), T1 (1/-), C2 (3/-), C3 (2/-), Lawf collaterals (5) and epithelial glia (6/-) (Rivera-Alba et al., 2011). |
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Links to Extrernal Ontologies
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VFB:FBbt_00003741
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Alleles (FBal) | PHENOTYPE_MANIFEST_IN | 1 | | Insertions (FBti) | EXPRESSION_STAGE_TISSUE_POSITION | 3 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Alleles | | Insertions | Constructs |
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lamina wide-field 1 neuron (all annotations which use CV term, excluding "NOT" statements) | 5 | 3 | 3 | 9 | lamina wide-field 1 neuron | absent | larval stage | 1 | -- | -- | -- |
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Relationships