Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Term | mushroom body output neuron 11 | ID (Ontology) | FBbt:00100246 (Fly Anatomy) |
| Definition | A GABAergic neuron whose cell body is located on the inferior neuropils (Tanaka et al., 2008; Aso et al., 2014). The cell body fiber runs posteriorly and bifurcates laterally and medially (Tanaka et al., 2008). The lateral branch arborizes in the lateral-most spur area of the gamma lobe (slice 1) and the core of the pedunculus (Tanaka et al., 2008), where it receives input from Kenyon cells (Aso et al., 2014). Its axon projects bilaterally to the alpha and beta lobes and contralaterally to the core of the pedunculus and, to a lesser extent, to the crepine. In the alpha lobe slice 3, its terminals are enriched in the surface layer. There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020). It receives input from the octopaminergic VPM3 and VPM4 neurons in the mushroom body gamma lobe slice 1 (Sayin et al., 2019). It synapses onto proximal parts of MBON01 and distal parts of MBON04 (Felsenberg et al., 2018). In the alpha lobe, it has feedforward connections onto MBON07 and MBON14 (Li et al., 2020). It is involved in food odor attraction (Sayin et al., 2019) and multiple stages of reward and punishment memory (Ichinose et al., 2021). It develops from the larval MBON-d1 (Truman et al., 2023).[ FlyBase:FBrf0205263 FlyBase:FBrf0227179 FlyBase:FBrf0240371 FlyBase:FBrf0243986 FlyBase:FBrf0248215 FlyBase:FBrf0248476 FlyBase:FBrf0255928 ] | ||
| Also Known As | "MB-MVP2" ; "MBON-11" ; "MBON-gamma1pedc>alpha/beta" (for all, see Synonyms field below) | ||
| Comment | Names are assigned according to the area of the mushroom body they arborize, as detailed in Tanaka et al. (2008). | ||
| Links to Extrernal Ontologies | |||
| VFB:FBbt_00100246 | |||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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adult head |__adult brain________________________________ adult central nervous system | |__adult brain________________________________| brain | |__adult brain________________________________| interneuron | |__primary interneuron________________________| GABAergic neuron | |__adult GABAergic neuron_____________________| adult neuron | |__adult GABAergic neuron_____________________| primary neuron | |__primary interneuron________________________| adult mushroom body output neuron | |__adult typical mushroom body output neuron__| CNS neuron | |__supraesophageal ganglion neuron____________| mushroom body output neuron 11 26 rec. |
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supraesophageal ganglion neuron adult typical mushroom body output neuron primary interneuron adult GABAergic neuron |
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| Develops from | larval mushroom body output neuron d1 | ||
| Part of | adult brain | ||
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FlyBrain_NDB:10471 VFB:FBbt_00100246 |
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