FB2024_03 , released June 25, 2024
Allele: Ecol\lexAR43D01
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General Information
Symbol
Ecol\lexAR43D01
Species
E. coli
Name
FlyBase ID
FBal0351539
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
PBac{R43D01-lexA}
Also Known As
R43D01-LexA
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kallman et al., 2015)
Progenitor genotype
Carried in construct
PBac{R43D01-lexA}
Cytology
Description

1157bp of genomic DNA including the GMR43D01 fragment drives expression of lexA::p65.

(Kallman et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
GMR43D01
Encoded product / tool
lexA::p65
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | male
      adult fruitless aDT-b (male) neuron
      (Kallman et al., 2015)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.13XLexAop2.Venus with 635 nm (red) light) of Ecol\lexAR43D01 cells in adult males results in a significant, rapid hyperpolarization of P1 neurons, compared to controls.

      (Kallman et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lexAR43D01
      Name Synonyms
      Secondary FlyBase IDs
        References (2)