UAS regulatory sequences drive expression of a short inverted repeat.
FlyBase curator comment: 'coenzyme Q10 deficiency disease' subtype 'primary coenzyme Q10 deficiency 4' is associated with gene COQ8. Coq8GL01574, when driven in pericardial nephrocytes (Scer\GAL4Ugt36A1.PK) serves to model the nephrotic syndrome phenotype of 'primary coenzyme Q10 deficiency 4'.
Adult flies expressing CG32649GL01574 under the control of Scer\GAL4Dot.PK display nephrocyte functional defects (measured by uptake assays) but their adult lifespan is comparable to controls.
Females heterozygous for CG32649GL01574 and Scer\GAL4mat.αTub67C.T:Hsim\VP16 crossed to CG32649GL01574 males results in: 79% hatching; non-maternal effect.