UAS regulatory sequences drive expression of a short inverted repeat.
Expression of domeHMS00647 under the control of Scer\GAL4NPF.1 (but not Scer\GAL4NP7175) interferes with satiety perception as it increases attraction to food cues in fed adult flies so it is comparable to the response observed in their starved counterparts as well as starved controls (and higher than in fed controls). It also results in increased food intake, higher adult body weight and increased fat deposition.
Expression of domeHMS00647 under the control of Scer\GAL4VGAT.PF results in small, slim flies, as quantified by a reduction in wing area. These flies show a significant decrease in triacylglycerol levels compared to controls.