FB2024_02 , released April 23, 2024
Allele: Dmel\mAcon1UAS.cPa
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General Information
Symbol
Dmel\mAcon1UAS.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Phillips
FlyBase ID
FBal0212658
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of wild-type Acon.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adulthood-only expression of mAcon1UAS.cPa under the control of Scer\GAL4elav.Switch.PO, induced by RU486 feeding, increases lifespan and increases memory(aversive olfactory conditioning assays) in middle-aged individuals (30 days old), but not young individuals (10 days old).

Expression during adulthood of mAcon1UAS.cPa under the control of one copy of Scer\GAL4Mef2.247.Switch leads to increased memory in middle-aged individuals; expression for only 7 days does not. Expression during adulthood of mAcon1UAS.cPa under the control of two copies of Scer\GAL4Mef2.247.Switch leads to increased memory in young and middle-aged individuals.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
AconScer\UAS.cPa
AconUAS.cPa
mAcon1UAS.cPa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Phillips
Secondary FlyBase IDs
    References (2)