FlyBase Allele Report: Dmel\sog[supersog1.UAS]

General Information

Symbol

Dmel\sog^{supersog1.UAS}

Species

D. melanogaster

Name

FlyBase ID

FBal0104936

Feature type

allele

Associated gene

Dmel\sog

Associated Insertion(s)

Carried in Construct

P{UAS-supersog.1}

Key Links

Transgenic product class

inframe_deletion

(Yu et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Yu et al., 2000)

Mutagen

in vitro construct

(Yu et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-supersog.1}

Cytology

Description

UAS regulatory sequences drive expression of a truncated form of sog that includes the CR1 domain plus another 114 amino acids (and contains an additional 33 amino acids derived from vector sequences at the C-terminus).

(Yu et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

sog

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004, Yu et al., 2000)

visible, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

visible, with Scer\GAL4^en-e16E

(Yu et al., 2004)

visible, with Scer\GAL4^ptc-559.1

(Evans et al., 2009)

Phenotype Manifest In

antenna, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

eye, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

wing, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004)

wing cell, with Scer\GAL4^ptc-559.1

(Evans et al., 2009)

wing vein, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004, Yu et al., 2000)

wing vein, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

wing vein, with Scer\GAL4^en-e16E

(Yu et al., 2004)

wing vein L2, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004, Yu et al., 2000)

wing vein L2, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

wing vein L3, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004, Yu et al., 2000)

wing vein L3, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

wing vein L4, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004, Yu et al., 2000)

wing vein L4, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

wing vein L4, with Scer\GAL4^en-e16E

(Yu et al., 2004)

wing vein L5, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004, Yu et al., 2000)

wing vein L5, with Scer\GAL4^dpp.blk1

(Yu et al., 2000)

wing vein L5, with Scer\GAL4^en-e16E

(Yu et al., 2004)

Detailed Description

Statement

Reference

Expression of sog^{supersog1.Scer\UAS} with Scer\GAL4^ptc-559.1 causes loss of the intervein area between L4 and L5.

(Evans et al., 2009)

Expression of sog^{supersog1.Scer\UAS} under the control of Scer\GAL4^Bx-MS1096 compression of the anterior/posterior axis in the wing, resulting in fusion of veins L2 and L3 and of L4 and L5, significant loss of wing veins and a modest reduction in overall wing size. Expression of sog^{supersog1.Scer\UAS} under the control of Scer\GAL4^en-e16E results in a severe loss of vein phenotype in the wing in which the remaining segments of veins L4 and L5 are nearly fused.

(Yu et al., 2004)

Expression of sog^{supersog1.Scer\UAS} under the control of Scer\GAL4^dpp.blk1 results in a phenotype nearly indistinguishable from that of dpp^d6/dpp^hr27 mutants. The flies have vein deletions, reduced eyes and shortened antennae. Wing veins L2 and L3 and wing veins L4 and L5 are closer together than normal or fused. Expression of sog^{supersog1.Scer\UAS} under the control of Scer\GAL4^Bx-MS1096 results in wing vein truncations. Wing veins L2 and L3, wing veins L3 and L4, and wing veins L4 and L5 are closer together than normal or fused.

(Yu et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^A9/sog^{supersog1.UAS} is a suppressor of visible phenotype of Scer\GAL4^A9, gbb^UAS.cKa

(Yu et al., 2000)

Scer\GAL4^A9/sog^{supersog1.UAS} is a suppressor | partially of visible phenotype of Scer\GAL4^A9, dpp^UAS.cHa

(Yu et al., 2000)

Other

Statement

Reference

Scer\GAL4^Bx-MS1096, Xlae\noggin^UAS.cYa, sog^{supersog1.UAS} has visible phenotype

(Yu et al., 2000)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^ptc-559.1, sog^{supersog1.UAS} has wing cell phenotype, suppressible by kek5^fe148/kek5^fe148

(Evans et al., 2009)

NOT Enhancer of

Statement

Reference

Scer\GAL4^A9/sog^{supersog1.UAS} is a non-enhancer of wing phenotype of Scer\GAL4^A9, tkv^{Q199D.UAS.Tag:HA}

(Yu et al., 2000)

Suppressor of

Statement

Reference

Scer\GAL4^A9/sog^{supersog1.UAS} is a suppressor of wing phenotype of Scer\GAL4^A9, gbb^UAS.cKa

(Yu et al., 2000)

Scer\GAL4^A9/sog^{supersog1.UAS} is a suppressor of wing vein | ectopic phenotype of Scer\GAL4^A9, dpp^UAS.cHa

(Yu et al., 2000)

Scer\GAL4^A9/sog^{supersog1.UAS} is a suppressor of wing cell phenotype of Scer\GAL4^A9, dpp^UAS.cHa

(Yu et al., 2000)

Scer\GAL4^A9/sog^{supersog1.UAS} is a suppressor | partially of wing phenotype of Scer\GAL4^A9, dpp^UAS.cHa

(Yu et al., 2000)

NOT Suppressor of

Statement

Reference

Scer\GAL4^A9/sog^{supersog1.UAS} is a non-suppressor of wing phenotype of Scer\GAL4^A9, tkv^{Q199D.UAS.Tag:HA}

(Yu et al., 2000)

Other

Statement

Reference

Scer\GAL4^Bx-MS1096, sog^{supersog1.UAS}, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, Xlae\noggin^UAS.cYa, sog^{supersog1.UAS} has wing phenotype

(Yu et al., 2000)

Scer\GAL4^Bx-MS1096, Xlae\noggin^UAS.cYa, sog^{supersog1.UAS} has wing vein phenotype

(Yu et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The loss of intervein area between L4 and L5 resulting from expression of sog^{supersog1.Scer\UAS} with Scer\GAL4^ptc-559.1 in the wing is suppressed in a homozygous kek5^fe148 mutant background.

(Evans et al., 2009)

Co-expression of sog^{supersog1.Scer\UAS} partially suppresses the broadened wing phenotype caused by expression of dpp^Scer\UAS.cHa under the control of Scer\GAL4^A9 and almost completely suppresses the conversion of intervein regions into veins. Suppresses the wing phenotype caused by expression of gbb^Scer\UAS.cKa under the control of Scer\GAL4^A9. Expression of tkv^{Q199D.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^A9 causes a wing phenotype. This phenotype is not altered by co-expression of sog^{supersog1.Scer\UAS}.

(Yu et al., 2000)

Xenogenetic Interactions

Statement

Reference

Co-expression of sog^{supersog1.Scer\UAS} and Xlae\noggin^Scer\UAS.cYa under the control of Scer\GAL4^Bx-MS1096 results in tiny wings with a single fused central vein.

(Yu et al., 2000)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

sog^{supersog1.Scer\UAS}

sog^{supersog1.UAS}

Name Synonyms

Secondary FlyBase IDs

References (4)

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