FB2024_03 , released June 25, 2024
Aberration: Dmel\In(1)sc7
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General Information
Symbol
In(1)sc7
Species
D. melanogaster
Name
FlyBase ID
FBab0004196
Feature type
chromosomal_inversion
Computed Breakpoints include

1B4;6D8

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Florence, 1999.7.22, Lindsley and Zimm, 1992, Lindsley and Grell, 1968)
Breakpoints

1B4-1B6;5D3-5D6

(Lindsley and Grell, 1968)

1B3-1B4;6D8

(Florence, 1999.7.22, Lindsley and Zimm, 1992)
Causes alleles
sc7
(Gomez-Skarmeta et al., 1995, Ray and Rodrigues, 1994, Lindsley and Zimm, 1992, Cubas et al., 1991, Campuzano et al., 1985)
Carries alleles
Nopa33b
(Rice et al., 2015)
Transposon Insertions
Formalized genetic data

bk1 hits sc << bk2

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Campuzano et al., 1985, Carramolino et al., 1982)

Left breakpoint between DNA coordinates -1.8 and -5.9 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scĪ² segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).

Comments on Cytology

Cytology determined by Lefevre.

(Lindsley and Zimm, 1992)

2.5 to 3.1kb DNA is deleted in the neighbourhood of the distal chromosome breakpoint.

(Campuzano et al., 1985)

Cytology determined by Schultz.

(Lindsley and Grell, 1968)

Left limit of break 1 from polytene analysis (FBrf0020044) Right limit of break 1 from polytene analysis (FBrf0109188) Limits of break 2 from polytene analysis (FBrf0109188)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Pdfr
(Lear et al., 2005)
sc
(Campuzano et al., 1985)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
eag
(Lear et al., 2005)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Homozygous females show a strong loss of tergite chaetae.

    (Mari-Beffa et al., 1991)

    Normal disjunction and 33% recombination in In(1)sc7/+ female, 26% secondary nondisjunction and 27% recombination in In(1)sc7/+/Y female (Grell, 1962, Genetics 47: 1737-54). wa removable from the inversion by double crossing over in triploid.

    Stocks (9)
    Notes on Origin
    Discoverer

    Dubinin, 1929.

     

    on a wa chromosome

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    In(1)sc7
    (Ray and Rodrigues, 1994)
    In(1)sc7
    (Rice et al., 2015, Carhan et al., 2005, Lear et al., 2005)
    sc7
    (Mari-Beffa et al., 1991)
    Name Synonyms
    Secondary FlyBase IDs
      References (21)