FB2024_03 , released June 25, 2024
Aberration: Dmel\In(1)sc29
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General Information
Symbol
In(1)sc29
Species
D. melanogaster
Name
FlyBase ID
FBab0004186
Feature type
chromosomal_inversion
Computed Breakpoints include

1B3-1B4;13A2-13A5

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Drysdale et al., 1991, Hardy et al., 1984, Lindsley and Grell, 1968)
Breakpoints

1B;13A2-13A5

(Drysdale et al., 1991, Hardy et al., 1984, Lindsley and Grell, 1968)

1A5-1B2;13A1-13A6;[1A5-1B2];[13A1-13A6];

(Cook, 2008.12.11)
Causes alleles
sc29
(Lindsley and Zimm, 1992, Campuzano et al., 1985)
eagsc29
(Wu et al., 2010, Dubin et al., 1998, Hevers and Hardie, 1995, Leibovitch et al., 1995, Drysdale et al., 1991, Hardie, 1991, Warmke et al., 1991)
Pdfrsc29
(Lear et al., 2005)
Carries alleles
Transposon Insertions
Formalized genetic data

l(1)sc << bk1 << sc << bk2 hits eag

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Drysdale et al., 1991, Campuzano et al., 1985, Carramolino et al., 1982)

Breakpoint between DNA coordinates -6.1 and -6.4 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scĪ² segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).

Comments on Cytology

The distal breakpoint is between 1A5,6 and 1B1,2 and the proximal breakpoint is between 13A1,2 and 13A5,6.

(Cook, 2008.12.11)

Cytology determined by Raffel.

(Lindsley and Grell, 1968)

Left limit of break 1 from complementation mapping against l(1)sc (citation unavailable) Right limit of break 1 from complementation mapping against sc (FBrf0042024) Left limit of break 2 from complementation mapping against eag (FBrf0054163) Right limit of break 2 from polytene analysis (FBrf0040961)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
eag
(Lear et al., 2005, Leibovitch et al., 1995, Hardie, 1991)
Pdfr
(Lear et al., 2005)
sc
(Campuzano et al., 1985)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Homo- and hemizygotes show ether induced leg shaking and electrophysiological defect characteristic of eag mutations.

    (Drysdale et al., 1991)

    Homozygous females show a strong loss of tergite chaetae.

    (Mari-Beffa et al., 1991)
    Stocks (3)
    Notes on Origin
    Discoverer

    Agol, 1930.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    In(1)sc29
    (Warmke et al., 1991)
    In(1)sc29
    (Cook, 2008.12.11, Haigh and Lloyd, 2007)
    eagsc29
    (Lear et al., 2005)
    sc29
    (Mari-Beffa et al., 1991)
    Name Synonyms
    Secondary FlyBase IDs
      References (19)