FlyBase Aberration Report: Dmel\Df(2L)TW158

General Information

Symbol

Df(2L)TW158

Species

D. melanogaster

Name

Deficiency (2L) Ted Wright

FlyBase ID

FBab0001647

Feature type

chromosomal_deletion

Also Known As

Df(2L)158

Computed Breakpoints include

37B2-37B8;37E2

Features within 37B2--37E2

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Stathakis et al., 1995, Wright et al., 1981, Wright et al., 1976)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Zak, 1998, Tavosanis et al., 1997, Palopoli and Wu, 1996, Pauli et al., 1995, Stern et al., 1990, Wright et al., 1981, Wright et al., 1976)

Breakpoints

37B2-37B8;37E2-37F4

(Zak, 1998, Palopoli and Wu, 1996, Pauli et al., 1995, Stern et al., 1990, Wright et al., 1981, Wright et al., 1976)

37B2--8;[]

(Tavosanis et al., 1997)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)37Bi << bk1 << l(2)37CDf << l(2)37Dk << bk2 << ref(2)P

Genetic mapping information

Comments

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)

Breakpoint(s) molecularly mapped

(Rutledge et al., 1992, Contamine et al., 1989)

Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0028752) Left limit of break 2 from polytene analysis (FBrf0028752) Right limit of break 2 from non-inclusion of ref(2)P (citation unavailable)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

amd

(Wright et al., 1976)

brat

(Brittnacher and Ganetzky, 1983)

Ddc

(Palopoli and Wu, 1996, Wright et al., 1976)

esc

(Wright et al., 1976)

hook

(Wright et al., 1976)

l(2)37CDa

(Wright et al., 1976)

l(2)37CDb

(Wright et al., 1976)

l(2)37CDc

(Wright et al., 1976)

l(2)37CDd

(Wright et al., 1976)

l(2)37CDe

(Wright et al., 1976)

l(2)37CDf

(Wright et al., 1976)

l(2)37Db

(Brittnacher and Ganetzky, 1983, Wright et al., 1976)

l(2)37Dc

(Brittnacher and Ganetzky, 1983, Wright et al., 1976)

l(2)37De

(Brittnacher and Ganetzky, 1983, Wright et al., 1976)

l(2)37Di

(Brittnacher and Ganetzky, 1983, Wright et al., 1976)

l(2)37Dk

(Wright et al., 1976)

l(2)37Dl

(Wright et al., 1976)

l(2)37Dm

(Wright et al., 1976)

l(2)37Ea

(Butler et al., 2001)

RanGAP

(Palopoli and Wu, 1996)

swm

(Gay and Contamine, 1993, Brittnacher and Ganetzky, 1983, Wright et al., 1976)

Top2

(Palopoli and Wu, 1996)

γTub37C

(Schnorrer et al., 2002, Tavosanis et al., 1997)

Partially deleted / disrupted

Molecular Data

Completely deleted

mRpL13

(Marygold et al., 2007)

RpL30

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

amos

(Ganetzky, 1977, Wright et al., 1976)

barr

(Butler et al., 2001)

(Wright et al., 1976)

CadN

(Wright et al., 1976)

crc

(Ganetzky, 1977, Wright et al., 1976)

Cul2

(BDGP Project Members, 1994-1999)

l(2)37Fc

(Butler et al., 2001)

l(2)38Ab

(Butler et al., 2001)

l(2)01528

(BDGP Project Members, 1994-1999)

l(2)03832a

(BDGP Project Members, 1994-1999)

(Ganetzky, 1977, Wright et al., 1976)

M(2)39F

(Wright et al., 1976)

mAcon1

(BDGP Project Members, 1994-1999)

(Ganetzky, 1977, Wright et al., 1976)

rdo

(Wright et al., 1976)

RpS26

(Wright et al., 1976)

spi

(BDGP Project Members, 1994-1999)

tup

(Zak, 1998)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

No effect on In(1)w^m4h position-effect variegation.

(Wustmann et al., 1989)

Lethal over Df(2L)E71. Lethal over Df(2L)E55.

(Wright et al., 1976)

NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22.

(Burnette et al., 1999)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Stocks (3)

Bloomington

3784

Df(2L)TW158, cn¹ bw¹/CyO

Kyoto

107232

Df(2L)TW158, cn¹ bw¹/CyO

101365

CyO, Duox^Cy dpy^lv1 pr¹ cn² / Df(2L)TW158, cn¹ bw¹

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

The Df(2L)TW158 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

(Mason et al., 2004)

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

158

(Ganetzky, 1977)

DF(2l)TW158

(Jordan et al., 2006)

Df(2L)158

(Brittnacher and Ganetzky, 1983, Wright et al., 1981, Wright et al., 1976, Wright et al., 1976)

Df(2L)TW158

(Casso et al., 2008)

Name Synonyms

Deficiency (2L) Ted Wright

Secondary FlyBase IDs

FBab0001564

References (31)

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